Am J Clin Case Rep. 2023;4(2):AJCCR-04-1084 | Open Access
Introduction: Familial Adenomatous Polyposis (FAP), which has a very high tendency of progression to colorectal cancer, is mainly caused by ...
Am J Clin Case Rep. 2023;4(2):AJCCR-04-1083 | Open Access
Early onset necrotizing enterocolitis in full term newborn associated with placental chorangiosis: A case report
Necrotizing Enterocolitis (NEC) is a serious inflammatory disease that affects intestinal wall in premature infants. Full-term infants account for approximately 10% ...
Am J Clin Case Rep. 2023;4(2):AJCCR-04-1082 | Open Access
Congenital bronchogenic cyst
Background: Bronchogenic cysts are lesions of congenital origin derived from the primitive foregut and are the most prevailing primary cysts ...
Am J Clin Case Rep. 2023;4(2):AJCCR-04-1081 | Open Access
Bilateral chest injury in a single gunshot injury; right pleural breach with an open pneumothorax and a cavitary chest wall wound from an AK-47- a case report
Background: The effect of tissue injury depends not only on the muzzle kinetic energy, the distance from the muzzle to ...
Am J Clin Case Rep. 2023;4(2):AJCCR-04-1080 | Open Access
Skin metastases of malignant pleural mesothelioma
Background: Mesothelial cells are derived from the primitive embryonic mesoderm and line the pleurae and peritoneum. There are involved in ...
Am J Clin Case Rep. 2023;4(2):AJCCR-04-1079 | Open Access
Prevalence of Inguinal Hernia and Its Risk Factors In Adult Males Admitted to Surgical Wards of Wolaita Sodo Comprehensive Specialized Hospital, Wolaita Sodo, Ethiopia.
Background: An inguinal hernia is defined as the protrusion or passage of a peritoneal sac, with or without abdominal contents, ...
Am J Clin Case Rep. 2023;4(2):AJCCR-04-1078 | Open Access
Calcifying Fibrous Tumor within Lung Parenchyma: Case Report
Calcifying fibrous tumor is a rare benign neoplasm, with few cases reported within lung parenchyma. Due to its rarity and ...
Am J Clin Case Rep. 2023;4(1):AJCCR-04-1077 | Open Access
An Immunohistochemcial assessment of Endoglin (CD105) expression in Oral epithelial dysplasias and Oral Squamous cell carcinomas.
Introduction: Oral Squamous Cell Carcinoma (OSCC) is the eighth most common malignant epithelial neoplasm. Clinical studies suggest that 10% to 20% of ...
Am J Clin Case Rep. 2023;4(1):AJCCR-04-1076 | Open Access
Incidence of Tuberculosis and Sarcoidosis in Patients with Histopathologic Granulomatous Inflammation
Background: Granulomatous inflammation is a distinct form of chronic inflammation in response to a variety of infectious, autoimmune, toxic, allergic ...
Am J Clin Case Rep. 2023;4(1):AJCCR-04-1075 | Open Access
Submandibular Gland Involvement, As an Unusual and the Only Site of Breast Cancer Metastasis, Detected in FDG PET/CT Study
We present a rare case of solitary submandibular gland metastases in a 40 years old lady after being treated for invasive ...
Am J Clin Case Rep. 2023;4(1):AJCCR-04-1074 | Open Access
The Value of Colon Cancer Screening in Developing Countries
Objectives: Colorectal cancer is the third most diagnosed cancer worldwide and the second most common cause of cancer death. If ...
Am J Clin Case Rep. 2023;4(1):AJCCR-04-1073 | Open Access
Link between Two Decades of Oral Contraceptives and Bowel Infarction: A Case Report
Objectives: Partial or total necrosis of the bowel is a frequent cause of obstruction of the mesenteric artery or vein. ...
Am J Clin Case Rep. 2022;3(5):AJCCR-03-1072 | Open Access
Cholecystitis in Young Age due to Cholesterolosis: A Case Report Study
Background: Cholesterolosis of the gallbladder, is characterized by the accumulation of cholesterol esters and triglycerides in macrophages on the surface ...
Am J Clin Case Rep. 2022;3(5):AJCCR-03-1071 | Open Access
WPW Syndrome: Review of Literature
Wolff-Parkinson-White (WPW) disorder is a disorder where there is additional accessory electrical pathway in the heart. Wolff-Parkinson- White syndrome (WPW) ...
Am J Clin Case Rep. 2022;3(4):AJCCR-03-1070 | Open Access
Our Commitments and Efforts to Cancer Patients in Developing Countries
Am J Clin Case Rep. 2022;3(4):AJCCR-03-1069 | Open Access
A Huge Cystic Mesenteric Lymphangioma of Small Intestine Involving Ileum: An Unusual Cause of Abdominal Pain
Background: Lymphangioma of the small-bowel mesentery are very rare, and lymphangiomas in the jejunum or ileum are extremely rare, accounting ...
Am J Clin Case Rep. 2022;3(4):AJCCR-03-1068 | Open Access
Views on Racial and Ethnic Equality in Health Care and Research
The present article deals with the still existing inequalities in health care services and to a lesser extent in the ...
Am J Clin Case Rep. 2022;3(4):AJCCR-03-1067 | Open Access
Antibodies with Clinico-Immunological Mismatch: An Emerging Conundrum
Introduction: The field of Neuroimmunology is expanding rapidly with the advent of newer antibodies and their phenotypes. Considering the treatability ...
Am J Clin Case Rep. 2022;3(4):AJCCR-03-1066 | Open Access
A New Onset of Psychosis in a Patient with COVID-19
Psychiatric sequelae of the Severe Acute Respiratory Syndrome Coronavirus (COVID-19) such as depression and anxiety spectrum disorders have attracted a ...
Am J Clin Case Rep. 2022;3(3):AJCCR-03-1065 | Open Access
Challenges Facing Lung Cancer Patients Who Need Palliative and Supportive Care during COVID-19 Pandemic
Lung cancer is often associated with significant morbidity, and has been profoundly impacted by the global pandemic of severe acute ...
Am J Clin Case Rep. 2022;3(3):AJCCR-03-1064 | Open Access
Incidence and Treatment of Pain in Patients who Attend the Emergency Department of a Children’s Hospital in Dominican Republic, January - March, 2019
Pain, one of the most prevalent symptoms in pediatric patients who visit the emergency department, is frequently underestimated and managed ...
Am J Clin Case Rep. 2022;3(3):AJCCR-03-1063 | Open Access
Crohn’s Disease Concurrent with Hemoglobin E (HbE) Disease Manifested as Melaena with Severe Anaemia
Hemoglobin E (HbE) disease is an inherited autosomal recessive disorder presented as mild anaemia and occasionally a slightly enlarged spleen ...
Am J Clin Case Rep. 2022;3(3):AJCCR-03-1062 | Open Access
Secondary Membranous Nephropathy: “Full-House” Pattern in a Syphilis and Parvovirus B19 Coinfection
Introduction: The Syphilis can share many similarities with multiple autoinmune diseases, mostly when it evolves to secondary syphilis with its ...
Am J Clin Case Rep. 2022;3(3):AJCCR-03-1061 | Open Access
A Case of Type 1 Kounis Syndrome Induced by Angong Niuhuang Pill in a Patient Vaccinated with COVID-19 Vaccine
Kounis syndrome refers to an acute coronary syndrome, consequent to an allergic reaction. It results from mast cell degranulation with ...
Am J Clin Case Rep. 2022;3(2):AJCCR-03-1059 | Open Access
Emerging Infectious Agents: An Unusual Case of Metapneumovirus Pneumonia in an Adult Patient
Human Metapneumovirus (hMPV), a relatively new virus, is a common cause of acute respiratory infection, especially common in the pediatric ...
Am J Clin Case Rep. 2022;3(2):AJCCR-03-1058 | Open Access
M-TACE Caused a Massive Necrosis of Liver Metastasis from Submandibular Cancer: A Case Report
Approximately, 40 – 45 percent of submandibular gland tumors are malignant. Liver is one of the most common sites of distant metastatic ...
Am J Clin Case Rep. 2022;3(2):AJCCR-03-1057 | Open Access
Parathyroid Carcinoma Presented as a Consumptive Syndrome with Diarrhea
Parathyroid carcinoma (PC) is a rare condition in which severe hypercalcemia is frequently associated with a palpable cervical mass. The ...
Am J Clin Case Rep. 2022;3(2):AJCCR-03-1056 | Open Access
End-stage, Chicago/FBF Type I Achalasia in a Patient with Long-standing Untreated Dysphagia: Case Report and Pictorial Essay
We describe here the clinical history of a 52-year old woman presenting with a severe long-standing esophageal dysphagia of more ...
Am J Clin Case Rep. 2022;3(1):AJCCR-03-1053 | Open Access
Efficacy and Safety of Pharmacological Treatments for Pregnancy-Induced Hypertension: A Systematic Review and Network Meta-Analysis
Introduction: To conducted a Bayesian network meta-analysis to determine the efficacy, safety and precision of pharmacological treatment for pregnancyinduced hypertension (...
Am J Clin Case Rep. 2022;3(1):AJCCR-03-1055 | Open Access
Human Breast Milk to Heal Grandma: Just what the Doctor Ordered
The use of complementary and alternative medicine (CAM) is common amongst cancer patients. Evidence shows these treatment modalities may address ...
Am J Clin Case Rep. 2022;3(1):AJCCR-03-1054 | Open Access
An Update on the Status of the Most Prevalent Cancer Types in Western Africa and Their Management
Sub-Saharan countries have a very high burden of cancer and mortality, especially breast cancer, cervical cancer and those from an ...
Am J Clin Case Rep. 2022;3(1):AJCCR-03-1052 | Open Access
Negative Surgical Margins following Robot-assisted Radical Prostatectomy for Organ-Confined Prostate Cancer: What’s next?
Background: The majority of men undergoing Robot-Assisted Radical Prostatectomy (RARP) have pathological T2 disease with negative surgical margins. Nevertheless, some ...
Am J Clin Case Rep. 2022;3(1):AJCCR-03-1051 | Open Access
Scurvy: Cases of an Old Disease in Two Neurotypical Pediatric Patients in a Children's Hospital
Scurvy, caused by the dietary deficiency of vitamin C, is an uncommon disease among the pediatric population. In this report, ...
Am J Clin Case Rep. 2021;2(7):AJCCR-03-1050 | Open Access
Palliative Care for a Patient with Advanced Cervical Cancer - Case Report
Patients with advanced cancer are often affected by multiple symptoms, causing both physical and psychosocial suffering. Palliative care is a ...
Am J Clin Case Rep. 2021;2(7):AJCCR-03-1049 | Open Access
An Invasive Tumor Thrombus from Renal Cell Carcinoma in the Right Heart: Case Report
Renal Cell Carcinoma (RCC) with metastatic tumor thrombus and cardiac involvement is rare and has only been reported in a ...
Am J Clin Case Rep. 2021;2(7):AJCCR-02-1047 | Open Access
When Should Nanny Elbow be Considered Child Neglector Abuse?
Am J Clin Case Rep. 2021;2(7):AJCCR-02-1046 | Open Access
Green Urıne: A Rare Side Effect of Propofol in a Pediatric Case
Propofol is a short-acting intravenous sedative-hypnotic agent widely used to induce and maintain general anesthesia and sedation. A rare side ...
Am J Clin Case Rep. 2021;2(6):AJCCR-02-1045 | Open Access
Septic Arthritis with Candida in a Young Immunocompetent
Being part of the causes of septic arthritis, fungal arthritis is uncommon and is most often caused by the Candida ...
Am J Clin Case Rep. 2021;2(6):AJCCR-02-1044 | Open Access
An Unusual Cause of Chest Pain- Reflux Esophagitis Combined with Penetrating Aortic Ulcer
Am J Clin Case Rep. 2021;2(6):AJCCR-02-1043 | Open Access
Intracranial Extramedullary Hematopoiesis as “Ghost Tumor (Meningioma)”: First Case Report in Sickle Cell Disease and Review of Literature
Extramedullay hematopoiesis (EMH) is a common compensatory phenomenon to chronic hemolytic anemias. Commonly occurs in the liver, spleen, kidney, lymph ...
Am J Clin Case Rep. 2021;2(6):AJCCR-02-1042 | Open Access
Bowing of the Lower Limbs in a Newborn with Maternal Hypoparathyroidism: A Case Report
Introduction: Skeletal deformities cause difficulties in diagnosis and lead to uncertainty. Bowing of the lower limbs include a heterogeneous and ...
Am J Clin Case Rep. 2021;2(6):AJCCR-02-1041 | Open Access
Bilateral Symmetrical Serous Retinal Detachment as a Complication of HELLP Syndrome
The Incidence of Serous Retinal Detachment (SRD) in HELLP Syndrom is rare. Till now, there are just few published case ...
Am J Clin Case Rep. 2021;2(5):AJCCR-02-1040 | Open Access
Methylene Blue as Rescue Therapy for COVID-19 Patients Who Failed to Respond to other Therapies (Final Report)
Background: There is debate about the efficacy and safety of antiviral drugs for treatment of COVID-19 patients. In our first ...
Am J Clin Case Rep. 2021;2(5):AJCCR-03-1039 | Open Access
Non-operative Management of a Penetrating Splenic Injury: A Case Report
Introduction: Penetrating abdominal injury is usually managed by operative treatment: Non-operative treatment is rarely practiced by surgeons. The focus of ...
Am J Clin Case Rep. 2021;2(5):AJCCR-03-1038 | Open Access
Two Fulminant Tuberculosis Meningitis Cases without BCG Vaccine
Tuberculosis (TB) is still an important health problem in developing countries. It is a multisystemic disease that can affect many ...
Am J Clin Case Rep. 2021;2(5):AJCCR-03-1037 | Open Access
Primary Plasma Cell Leukaemia with Near-Tetraploidy: A Case Report
Plasma Cell Leukaemia (PCL) is an uncommon neoplasm of plasma cells, in which clonal plasma cells constitute > 20% of total ...
Am J Clin Case Rep. 2021;2(5):AJCCR-03-1036 | Open Access
Early T Cell Precursor Acute Lymphoblastic Leukaemia with t(1;12;13) (p22;p11.2;q14) in a 7-Month Old Girl
We describe a case of an infant diagnosed with Early T cell Precursor Acute Lymphoblastic Leukaemia (ETP-ALL). This leukaemia is ...
Am J Clin Case Rep. 2021;2(4):AJCCR-03-1034 | Open Access
Bier Spots on the Face: Case Report
Bier spots (BS) are asymptomatic, irregular, hypopigmented macules on an erythematous background and are usually found on the arms and ...
Am J Clin Case Rep. 2021;2(4):AJCCR-03-1033 | Open Access
An Unusual Case of Spontaneous Bilateral Orbital Hematoma
Scurvy is preventable disease caused by deficiency of vitamin C. It can present with non specific signs and symptoms. Therefore ...
Am J Clin Case Rep. 2021;2(4):AJCCR-03-1032 | Open Access
Sars-cov-2 Vaccination: What's the deal with Thrombosis?
Am J Clin Case Rep. 2021;2(2):AJCCR-03-1030 | Open Access
Massive Pleural Effusion with Bedside Echocardiographic Findings Suggestive of Pulmonary Thromboembolism after Left Internal Jugular Venous Catheterization: A Case Report
Bed-side echocardiography is critical for the diagnosis and management of undifferentiated shock. We report a case of massive hydrothorax after ...
Am J Clin Case Rep. 2021;2(2):AJCCR-02-1029 | Open Access
The Case of a Patient with Primary Amenorrhea and Arterial Hypertension
Objective: To highlight the importance in the etiological study of secondary arterial hypertension. Method: Describe a clinical case: clinical history, ...
Am J Clin Case Rep. 2021;2(2):AJCCR-02-1028 | Open Access
A Lady with an Ulcer on the Right Hand and Verrucous Lesions on the Li
A case of Ulcerative Lichen Planus (ULP) of a palm associated with hypertrophic lichen planus is reported. ULP is usually ...
Am J Clin Case Rep. 2021;2(2):AJCCR-02-1027 | Open Access
An Analyst’s Snapshot of Covid-era Sessions
Am J Clin Case Rep. 2021;2(2):AJCCR-02-1025 | Open Access
Management of Sleep Apnoea (due to nose block) in a Case of Thalassemia Major
This paper presents a case of Thalassemia Major (Beta Type), a major bleeding disorder where major surgery is usually avoided. ...
Am J Clin Case Rep. 2021;2(1):AJCCR-02-1024 | Open Access
Sexual Violence against Children in Brazil - The Importance of Immediate Reporting
Miziara ID, Galego Miziara CSM. Sexual Violence against Children in Brazil - The Importance of Immediate Reporting. Am J Clin ...
Am J Clin Case Rep. 2021;2(1):AJCCR-02-1023 | Open Access
Prevalence of Osteo-Sarcopenia and Osteosarcopenic Obesity in Healthy Ambulatory Subjects older than 45 years in France
This study aims to determine the prevalence of sarcopenia and osteopenia/osteoporosis among a population of 1508 healthy ambulatory subjects over 45 ...
Am J Clin Case Rep. 2021;2(1):AJCCR-02-1022 | Open Access
Adenocarcinoma of the Rete Testis: Interest of FDG PET/CT and Aggressive Surgical Management: A Case Report
Primary adenocarcinoma of the rete testis is a rare testicular tumor, classically associated with a poor prognosis. Due to its ...
Am J Clin Case Rep. 2021;2(1):AJCCR-02-1021 | Open Access
A Four-Vessel Cervical Artery Dissection Associated with a Tonic Seizure
The four-vessel cervical artery dissection is extremely rare. To our knowledge, its association with epilepsy has never been reported. A ...
Am J Clin Case Rep. 2021;1(1):AJCCR-01-1020 | Open Access
A Diagnostic Approach to Combined Hepatocellular- Cholangocarcinomas (cHCC-CCA)
Combined Hepatocellular-Cholangiocarcinomas (cHCC-CCA) are rare tumours, accounting for 2% to 5% of all primary liver cancers. cHCC-CCA is defined by the unequivocal ...
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1019 | Open Access
The First Case of Reactive Arthritis Associated with SARS-CoV-2-Infection in a 4-Year Old Child
Background: The novel coronavirus SARS‐CoV‐2 (severe acute respiratory syndrome coronavirus 2) and its associated disease COVID‐19 (Corona Virus Disease 19) has ...
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1018 | Open Access
Multiple Drug-Induced Liver Injury: Case Report
Drug-Induced Liver Injury (DILI) is a leading cause of acute liver failure and represents the first cause of fatalities related ...
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1017 | Open Access
Diffuse Gastro-intestinal Pneumatosis: Case Report
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1016 | Open Access
Giant Cystic Phaeochromocytoma: A Case Report
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1015 | Open Access
Caecal Volvulus and Jejunostomy: Challenging Diagnostic
Caecal volvulus represent the 20%-40% of all volvulus in colon, being the second localization in frequency after the sigmoid colon ...
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1014 | Open Access
Cryptococcal Meningitis as a Fatal Complication of Sarcoidosis
Cryptococcosis typically affects patients infected with immunodeficiency virus (HIV), but it may also occur in individuals under immunosuppressive treatment. Since ...
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1013 | Open Access
Characteristics of MTHFR C677T and A1298C Polymorphisms in Infertile Men and Impact of 3 Weeks of Yoga on MTHFR gene Expression: A Clinical Case Report
Introduction: One of the enzymes of the folate metabolism is methylenetetrahydrofolate reductase (MTHFR). The MTHFR gene polymorphism is correlated with ...
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1012 | Open Access
Mitochondrial Health-Role of Yoga: Clinical Implications
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1011 | Open Access
Early onset Streptococcal Pneumoniae Infection: An Unusual and Fatal Case
Streptococcal Pneumonia Infection In Neonates (SPIN) though rare still is a cause of neonatal sepsis and can mimic Group B ...
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1010 | Open Access
Idiopathic Sacrococcygeal Calcinosis Cutis
Calcinosis cutis is deposition of calcium and phosphorus in the skin. It is a rare benign disease. Idiopathic calcinosis cutis ...
Am J Clin Case Rep. 2020;1(2):AJCCR-01-1009 | Open Access
Hypnic Headache due to Bing and Neel Syndrome
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1005 | Open Access
Sudden Death by Myocardial Infarction in Children
We report the case of fatal myocardial infarction in a 14-year-old child. In these antecedents, he had an 11-year history ...
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1008 | Open Access
Vitrectomy with Temporal Approach Technique is Helpful in Removing Severe Diabetic Proliferative Membrane
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1007 | Open Access
Treatment of External Iliac Artery Pseudoaneurysm Developing after Percutaneous Closure of Ventricular Septal Defect
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1006 | Open Access
Unilateral Lower Limb Paresis Revealing Split Cord Malformation
Am J Clin Case Rep. 2020;1(1):ajccr-1004 | Open Access
A Case of Breast Cancer with Duodenal Metastasis
Am J Clin Case Rep. 2020;1(1):ajccr-1003 | Open Access
A Rare Cause of Adrenal Insufficiency in a Preterm Baby Born with an Extremely Low Birth Weight and Suspicious (Ambiguus) Genitalia: 3-Beta Hydroxysteroid Deficiency
In Congenital Adrenal Insufficiency (CAD), cortisol synthesis decreases or disappears as a result of deficiencies in enzymes that play a ...
Am J Clin Case Rep. 2020;1(1):ajccr-1002 | Open Access
BiPAP Is Not Always the Right Answer
Severe emphysema can result in spontaneous pneumothorax and even pneumomediastinum and cause acute dyspnea. Early recognition is important because routine ...
Am J Clin Case Rep. 2020;1(1):AJCCR-01-1001 | Open Access
Hereditary Hemochromatosis and Restrictive Cardiomyopathy Caused by Missense Mutation in HAMP and DSP: A Case Report
Background: The type 2 Hereditary Hemochromatosis (HH), caused by HJV or HAMP gene mutation, is an autosomal recessive disorder. HH caused ...