Ann Clin Pharmacol Toxicol. 2020;2(1):ACPT-02-1014 | Open Access
Chika J Mbah
Drug over dosage generally results in adverse effects (toxicity). Administration of the drug antagonist assists in reversing the adverse effects associated with the drug toxicity. Therapeutic blood or plasma concentration levels may be exceeded in the elderly, in individuals with reduced liver functions, in patients who raise the drug(s) doses as a result of tolerance and during chronic therapy. ... Read more
REVIEW ARTICLE Updated Aug 04, 2020 PDF
Ann Clin Pharmacol Toxicol. 2020;2(1):ACPT-02-1013 | Open Access
Suderio L and Perez AC
As COVID-19 spreads and increases worldwide since December 2019, the Scientists and the Medical Community are committed to find a treatment or even a vaccine. New therapies are being tested with “old” and well known medicaments but still there are many undesirable effects with each of them depending on your previous health status or age. We summarize a few ... Read more
REVIEW ARTICLE Updated Jul 27, 2020 PDF
Ann Clin Pharmacol Toxicol. 2019;1(3):ACPT-01-1012 | Open Access
Ashish Kumar Sarkar
An Ethnomedicinal survey was conducted on forestry and river regions Anuppur, tribal area of Madhya Pradesh, since this area is full of medicinal flora but their identification and continues study are lacking. Present aim of the study is to explore the tribal region having thousands of unidentified species. Ethnomedicinal data were collected using field observation and conductance of interviews of ... Read more
RESEARCH ARTICLE Updated Nov 04, 2019 PDF
Ann Clin Pharmacol Toxicol. 2019;1(3):ACPT-01-1011 | Open Access
Chika J Mbah
Chronic Obstructive Pulmonary Disease (COPD) is a preventable and treatable lung disease characterized by chronic obstruction of lung airflow that interferes with normal breathing and may be punctuated by periods of acute worsening of respiratory symptoms.
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EDITORIAL Updated Sep 13, 2019 PDF
Ann Clin Pharmacol Toxicol. 2019;1(2):ACPT-01-1010 | Open Access
Aziz S. Dobian and Hagib A. Al-Hagibi
The impact of chronic exposure of Mareb Crude Oil on the rate of oxygen consumption of the clam, Tivela Ponderosa was studied in the laboratory. The bivalve T. ponderosa is exposed to (0.5, 1 and 1.5) ml/l of Mareb Crude Oil. The oxygen consumption of bivalves T. ponderosa was controlled hourly at 5th and 10th day (every two and six hours). After 5 ... Read more
RESEARCH ARTICLE Updated Aug 07, 2019 PDF
Ann Clin Pharmacol Toxicol. 2019;1(2):ACPT-01-1009 | Open Access
Abdul Kader Mohiuddin
With over 50% of the adult population in the UK currently classified as overweight or obese, accompanied by an increased risk of type 2 diabetes and cardiovascular disease, finding more effective strategies to manage these conditions remains imperative. In 2016, World Health Organization (WHO) reported that more than 1.9 billion people in the world were overweight and over 650 million people were obese which has ... Read more
LETTER TO EDITOR Updated Aug 02, 2019 PDF
Ann Clin Pharmacol Toxicol. 2019;1(2):ACPT-01-1008 | Open Access
Mauro Luisetto, Ghulam Rasool Mashori and Kausar Rehman Khan
In today healthcare poisoning and toxicology play a relevant role in the management of patient life. Often severe cases can produce heavily consequence in patient and even exit us. To correctly treat this event are needed great organization between all services involved: emergency department, ICU, hospital pharmacy, toxicological lab, poison centre, central public institution and other.
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SHORT COMMUNICATION Updated Aug 02, 2019 PDF
Ann Clin Pharmacol Toxicol. 2019;1(2):ACPT-01-1007 | Open Access
Harikesh Maurya and Vikas Rao
Vitex negundo is a perennial plant belonging to family Verbenaceae highly distributed in the Himalayas region in India. The leaves, roots, fruits, and seeds have possessed hepatoprotective, antioxidant property, anti-inflammatory, anticancer and antioxidant properties. Generally, it required warm regions, common in waste places around villages, river banks, and most localities in the deciduous forests to grow. The V. negundo leaves ... Read more
REVIEW ARTICLE Updated Jul 11, 2019 PDF
Ann Clin Pharmacol Toxicol. 2019;1(1):ACPT-01-1006 | Open Access
García Darderes María Guadalupe, Gómez Acotto Claudia, D´Alessio Luciana and Roldán Emilio José Antonio
Introduction: Argentinean National Regulatory Health Authority became official member of the WHO Program for International Drug Monitoring in 1994.
However, the number of Adverse Drugs Reactions (ADRs) reported is still very low. Programs in Healthcare Professionals (HCP) in other countries showed that after surveys the knowledge and awareness about pharmacovigilance reporting improved, and the number of reports increase (1 to 4).
... Read more
RESEARCH ARTICLE Updated Mar 20, 2019 PDF
Ann Clin Pharmacol Toxicol. 2019;1(1):ACPT-01-1005 | Open Access
Vijai Lakshmi and Arvind Kumar Srivastava
Achyranthes Aspera linn is a vital source of drugs from the ancient time. It is known as Chirchita in hindi is an indigenous herb found in India, It has been used in almost all the traditional system of medicine, Ayurveda, Unani, and Siddha. The tribal, rural, and other people of our country commonly use this herb in various ... Read more
RESEARCH ARTICLE Updated Feb 22, 2019 PDF
Ann Clin Pharmacol Toxicol. 2018;1(1):ACPT-01-1004 | Open Access
Jayaraman Rajangam, Kiran T and Lavanya O
The aim of this study was to screen the antiamnesic activity of metformin (MET) on scopolamine (SCOP)-induced amnesia in mice. Experiments were carried out on 20 adult albino mice, divided into 4 groups, and the experimental animals were treated for 14 days with 10 mg/kg MET orally. To induce amnesia, 3 mg/kg SCOP was administered intraperitoneally. Cognitive skills of the animals were ... Read more
RESEARCH ARTICLE Updated Nov 27, 2018 PDF
Ann Clin Pharmacol Toxicol. 2018;1(1):ACPT-01-1003 | Open Access
Sidharth Mehan, Rajesh Dudi, Manju Rajput, Krishna Ghimire
Neurological disorders are a heterogeneous group of diseases of the nervous system having different etiologies. Intracerebral hemorrhage (ICH) having a common final finding, i.e., cognitive and motor impairment, and this may occur as a result of multineurotransmitter deficits, decreased availability of intracellular molecules, and axonal transporters through which the different neurons communicate with each other to maintain neuronal excitation ... Read more
REVIEW ARTICLE Updated Apr 25, 2018 PDF
Ann Clin Pharmacol Toxicol. 2018;1(1):ACPT-01-1002 | Open Access
George Kordas and Eleni Efthimiadou
We developed polymeric nanocontainers consisting of a shell with pH, T, and redox sensitivity grafted with targeting groups such as folic acid, leuprolide, and so on to target breast and prostate cancers. The quadrupole stimuli-targeted nanocontainers were loaded with doxorubicin and cisplatin called Nano4Dox and Nano4Cis platforms, respectively. In this study, we report the herapeutic efficacy of these ... Read more
REVIEW ARTICLE Updated Mar 10, 2018 PDF
Ann Clin Pharmacol Toxicol. 2018;1(1):ACPT-01-1001 | Open Access
Most Fahmida Begum, Abu Syed Md Mosaddek, Farhana Alamgir, Rumana Alim, Rezina Karim and Mahfuza Nasrin
Background: The antibiotic resistance pattern of Salmonella is ever changing over time.
Objective: This study is a retrospective analysis of the rate of isolation of Salmonella Typhi and Salmonella Paratyphi A from blood culture and their antibiotic resistance pattern.
Methods: Blood cultures submitted in Uttara Adhunik ... Read more
RESEARCH ARTICLE Updated Apr 20, 2018 PDF