Clin J Pharmacol Pharmacother. 2023;2(1):CJPP-02-1011 | Open Access
Sachin Tadge , Makarand Gambhire and Abhijit Kulkarni
The review delves into the existing ADR reporting systems, including the involvement of healthcare professionals and the growing role of patient-driven reporting initiatives. It examines the strengths and weaknesses of these systems and emphasizes the need for enhanced reporting practices to capture a comprehensive range of adverse reactions. Challenges in ADR reporting, such as underreporting, reporting bias, and difficulties in ... Read more
REVIEW ARTICLE Updated Sep 15, 2023 PDF
Clin J Pharmacol Pharmacother. 2021;1(1):CJPP-01-1010 | Open Access
Navinder Jassil*, Gino Chiappetta and Patricia Seuffert
Objective: To assess whether restrictions in medical care related to the impact of the Coronavirus 2019 (COVID-19) pandemic affected fracture incidence due to postponed denosumab therapy and to identify ways to adapt to interruptions in osteoporosis therapy during the pandemic.
Methods: We reviewed the records of a 64 year old female diagnosed in 2018 with osteoporosis undergoing treatment with denosumab until the pandemic ... Read more
RESEARCH ARTICLE Updated Jan 06, 2021 PDF
Clin J Pharmacol Pharmacother. 2020;1(1):CJPP-01-1009 | Open Access
Michel Bourin*
Treatment of bipolar depression is not achieved with conventional antidepressants. In recent years, certain antipsychotics have been used successfully, including quetiapine, which has gradually become the standard treatment.
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MINI REVIEW Updated Dec 31, 2020 PDF
Clin J Pharmacol Pharmacother. 2019;1(2):CJPP-02-1008 | Open Access
Sandeep Dhull, Ishu, Mini Dahiya, Monika Kadian and Monu Yadav
The study highlighted the authentication, identification and characterization of canola oil (Brassica napus; Brassicaceae), corn oil (Zea mays; Poaceae) and cotton seed oil (Gossypium hirsutum; Malvaceace) using Gas Chromatography-Mass Spectroscopy (GC-MS) (for phytoconstituents identification), Fourier Transform Infrared (FTIR) Spectroscopy (for structure elucidation) and Ultra Violet (UV) spectroscopy (for solubility studies). In GC-MS analysis18, 19 and 26 compounds were identified in canola oil, ... Read more
RESEARCH ARTICLE Updated Jun 20, 2019 PDF
Clin J Pharmacol Pharmacother. 2019;1(2):CJPP-02-1007 | Open Access
Noreen Samad and Kinza Hafeez
Mammary duct ectasia is described by persistent inflammation and changes of fibrosis which directs to blockage of debris within the mammary duct. Its characteristics imitates to that of invasive carcinoma. It mostly occurs in females at menopause or after menopause, but rare in children and men. Here we present a case report 37 years old lady having hyperprolactinemia, who came with ... Read more
CASE REPORT Updated Jun 20, 2019 PDF
Clin J Pharmacol Pharmacother. 2019;1(2):CJPP-02-1006 | Open Access
Cameron YS Lee and Jon B Suzuki
Purpose: The authors examined whether a novel alternative treatment regimen that is opioid-free administered preemptively 3 days prior to block bone graft surgery of the mandible has a preemptive analgesic effect on the intensity of pain at the graft harvest site during the 72-hour postoperative period.
Materials and methods: This qualitative prospective pilot study was conducted in a single office ... Read more
RESEARCH ARTICLE Updated Feb 13, 2019 PDF
Clin J Pharmacol Pharmacother. 2019;1(1):CJPP-01-1005 | Open Access
Hui-qin XU, Li-Wei HE, Ying-yue DU, Shu Zhang
The orthogonal test method was used to investigate the effects of solvent volume fraction, extraction time and solvent on the extraction process. The results showed that the best extraction process of the total lignans in Radix Isatidis is 70% ethanol, the extraction time is 2 h, and the amount of solvent is 8 times. The inhibitory effect of the total lignans of Radix ... Read more
RESEARCH ARTICLE Updated Feb 13, 2019 PDF
Clin J Pharmacol Pharmacother. 2018;1(1):CJPP-01-1004 | Open Access
Amin S, Mishra V, Desai Mira and Solanki Rajesh
Objectives: To evaluate Adverse Drug Reactions (ADRs) pattern of antitubercular drugs and its impact on MDR & XDR-TB patients.
Material & methods: An observational, continuous, retrospective & prospective, multi-centered study was carried out in MDR & XDR-TB patients enrolled for DOTS-PLUS regimen at Department of Pulmonary Medicine, Civil Hospital, Ahmedabad, over a period of 24 months from October 2015 to September 2017. ... Read more
RESEARCH ARTICLE Updated Dec 26, 2018 PDF
Clin J Pharmacol Pharmacother. 2018;1(1):CJPP-01-1003 | Open Access
Garro MA, Urizar E, Lazkano A, Zubillaga E and Querejeta R
Over the last few decades, the use of β-blockers has improved the clinical condition of patients with heart failure. However, the molecular mechanisms involved remain far from being completely understood. Adenylyl Cyclases (AC) are the major effectors of cardiac β-adrenergic receptors. Different functions have been attributed to their isoforms in relation to heart failure, with the AC5 isoform ... Read more
RESEARCH ARTICLE Updated Dec 19, 2018 PDF
Clin J Pharmacol Pharmacother. 2018;1(1):CJPP-01-1002 | Open Access
Shawqi Hussien Alawdi
Background: Metabolic Syndrome (MS) is a disorder defined by interconnected obesity-related risk factors that increase the risk of cardiovascular diseases, and diabetes mellitus in addition to several diseases. Several medications may increase the risk of MS by affecting lipid or glucose metabolism as well as weight gain or insulin resistance.
Objective: The present study aimed to investigate the effects ... Read more
RESEARCH ARTICLE Updated Dec 18, 2018 PDF
Clin J Pharmacol Pharmacother. 2018;1(1):CJPP-01-1001 | Open Access
Ivanka Atanasova, Dzhem Farandzha, Lubomir Spassov and Dimiter Terziivanov
Immunosuppression following solid organ transplantation is important therapy for the survival of both allograft and patient. After Orthotopic Liver Transplantation (OLT) many patients are treated by emulsified cyclosporine (Neoral®). 20 patients (8 adults and 12 children) who were on Neoral® postorthotopic liver transplantation over a 5 year period were studied (2004-2009). All patients received Neoral® twice daily orally at 08:00 AM and ... Read more
RESEARCH ARTICLE Updated Sep 06, 2018 PDF