International, Peer Reviewed, Open Access Journal

Annals of Integrative Molecular Medicine
(ISSN: 2690-0319)

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Annals of Integrative Molecular Medicine

Annals of Integrative Molecular Medicine (ISSN 2690-0319) s a peer- reviewed, open access, scientific journal published by Medtext Publications with an aim to highlights the work on biological, molecular, biomedicine research.

Journal Features

Open Access

All the articles will be published under Open Access model.

Peer Review

Our editorial team performs strict peer-review process.

Publication Ethics

The journal follows standard guidelines to maintain transparency.

Submit Manuscript

The journal accepts all original articles, reviews and more.

About the Journal

Annals of Integrative Molecular Medicine (ISSN 2690-0319) is a peer- reviewed, open access, scientific journal published by Medtext Publications with an aim to highlights the work on biological, molecular, biomedicine research and providing useful source of dissemination in the form of Original articles, Review article, Case reports, Case series, Editorial, Perspectives, Short Communications, Surgical techniques on all related latest novel discovery, current innovations etc.,   Medtext Publications is one of emerging open access publishing company which is self- financed and does not receives funds from any government or institution. The journal finance is handled by fees received from authors and some from academic/institutional sponsors   We will ensure and strive that Annals of Integrative Molecular Medicine maintain the standard accordingly in peer review, Editing, publishing etc., and encourages our researchers, scientists, academicians, clinicians and other expertise to publish their work to our journal.   Medtext Publications works diligently on peer review process from reviewers among which two independent reviews are taken in to considerations. Since it is an open access, articles published by this journal are freely available on internet to read, download without subscribing and can visit infinite time.   Annals of Integrative Molecular Medicine aims to maintain the fast publishing service and also seeks to introduce Thematic Issue with emerging topics, current innovations, novel trends, new drug entity discoveries, treatment regimens and enhancing the journal citation. We highlight on quality with time and at least three weeks for acceptance and this is achieved by great support from our Editorial Board Members who are having a crucial role in the journal development, aid in reviewing assigned articles, exchanging their ideas and advising for journal growth and also contribute in manuscript submission.   Our ultimate goal is to provide broad spectrum of useful and reliable source of information on rare and common disorders from Epidemiology, Etiology, causes and Treatment and to make readers aware of Molecular Medicine.

Open Access - Annals of Integrative Molecular Medicine

Articles

Ann Integr Mol Med. 2023;3(1):AIMM-03-1011 | Open Access

To Explore the Effect of Bu Zhong Yi Qi Powder on the Levels of Inflammatory Factors IL-6 and TNF-α in Stable COPD Patients with Spleen-Lung Qi Deficiency Pattern

Xueqing Chen, Yanzhui Liu, Xianjun Ou and Jie Jia

Objective: Traditional Chinese Medicine (TCM) herbal formulae provide valuable therapeutic strategies. However, the active ingredients and mechanisms of action remain unclear for most of these formulae. Therefore, the identification of complex mechanisms is a major challenge in TCM research. Methods: This study used a network pharmacology approach to clarify the anti-inflammatory and cough suppressing mechanisms of ... Read more

RESEARCH ARTICLE Updated Apr 17, 2023   PDF

Ann Integr Mol Med. 2021;2(1):AIMM-02-1010 | Open Access

Alzheimer’s Disease is Driven by Beta-Amyloid Generated in the Amyloid Precursor Protein-Independent Pathway and Retained Intraneuronally: Research and Therapeutic Strategies in a New AD Paradigm

Vladimir Volloch1* and Sophia Rits-Volloch2,3

The present article describes a New Paradigm of Alzheimer’s disease (AD). In the Old Paradigm, formalized in the Amyloid Cascade Hypothesis (ACH) theory of AD, beta amyloid (Aβ) is produced, both in health and disease, solely in the amyloid precursor protein (βAPP) proteolytic/secretory pathway. Two βAPP cleavages are involved. First cleavage, by beta-secretase (Beta-site ... Read more

PERSPECTIVE Updated Jan 01, 0001   PDF

Ann Integr Mol Med. 2021;2(1):AIMM-02-1009 | Open Access

News from Mars: Two-Tier Paradox, Intracellular PCR, Chimeric Junction Shift, Dark Matter mRNA and Other Remarkable Features of Mammalian RNA-Dependent mRNA Amplification. Implications for Alzheimer’s Disease, RNA-Based Vaccines and mRNA Therapeutics

Vladimir Volloch1* and Sophia Rits-Volloch2,3

Molecular Biology, a branch of science established to examine the flow of information from “letters” encrypted into DNA structure to functional proteins, was initially defined by a concept of DNA-to-RNA-to-Protein information movement, a notion termed the Central Dogma of Molecular Biology. RNA-dependent mRNA amplification, a novel mode of eukaryotic protein-encoding RNA-to-RNA-to-Protein genomic information transfer, constitutes the extension of ... Read more

PERSPECTIVE Updated Feb 04, 2021   PDF

Ann Integr Mol Med. 2020;2(1):AIMM-02-1008 | Open Access

Alzheimers Disease Prevention and Treatment: Case for Optimism

Vladimir Volloch, Bjorn Olsen and Sophia Rits

A paradigm shift is under way in the Alzheimer’s field. A view of Alzheimer’s disease, AD, prevailing until now, the old paradigm, maintains that it is initiated and driven by the overproduction and extracellular accumulation of beta-amyloid, Aβ; a peptide assumed to be derived, both in health and disease, solely by proteolysis of its large ... Read more

PERSPECTIVE Updated Aug 12, 2020   PDF

Ann Integr Mol Med. 2020;2(1):AIMM-1007 | Open Access

Alzheimer’s Disease is Driven by Intraneuronally Retained Beta-Amyloid Produced in the AD-Specific, βAPP-Independent Pathway: Current Perspective and Experimental Models for Tomorrow

Vladimir Volloch1*, Bjorn Olsen1 and Sophia Rits2,3

A view of the origin and progression of Alzheimer’s disease, AD, prevailing until now and formalized as the Amyloid Cascade Hypothesis theory, maintains that the disease is initiated by overproduction of beta-amyloid, Aβ, which is generated solely by the Aβ precursor protein, βAPP, proteolytic pathway and secreted from the cell. Consequent extracellular accumulation of A&... Read more

PERSPECTIVE Updated Apr 08, 2020   PDF