International, Peer Reviewed, Open Access Journal

Clinical Cases in Medicine
(ISSN: 2770-2359)

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Clinical Cases in Medicine

Clinical Cases in Medicine(2770-2359) is an open access, multidisciplinary journal devoted to publish works on clinical cases and collection of cases within the field of medical and clinical discipline.

Journal Features

Open Access

All the articles will be published under Open Access model.

Peer Review

Our editorial team performs strict peer-review process.

Publication Ethics

The journal follows standard guidelines to maintain transparency.

Submit Manuscript

The journal accepts all original articles, reviews and more.

About the Journal

Journal serves as an unique reference for all clinical cases and builds a forum for upcoming researchers to explore more in the field. CCM mainly focuses on high quality and evidence-based articles, which are openly accessible to readers all over the world. Most Interesting and challenging cases are vastly accepted in the journal.

Open Access - Clinical Cases in Medicine

Editorial Board

Pervin Elvan Tokgun - Clinical Cases in Medicine

Pervin Elvan Tokgun

Pamukkale University School of Medicine
Turkey

Athanasia Papazafiropoulou - Clinical Cases in Medicine

Athanasia Papazafiropoulou

General Hospital of Piraeus “Tzaneio”
Greece

Theodora Papamitsou - Clinical Cases in Medicine

Theodora Papamitsou

Aristotle University of Thessaloniki
Greece

Theofilidis Antonis - Clinical Cases in Medicine

Theofilidis Antonis

Third Department Psychiatric Clinic of Aristotle University of Thessaloniki
Greece

Yuting Tan - Clinical Cases in Medicine

Yuting Tan

Massachusetts General Hospital, Harvard Medical School
United States

Giuseppe Lanza - Clinical Cases in Medicine

Giuseppe Lanza

University of Catania
Italy

Berna Kuter - Clinical Cases in Medicine

Berna Kuter

Izmir Democracy University
Turkey

Maria Piagkou - Clinical Cases in Medicine

Maria Piagkou

National and Kapodistrian University of Athens (NKUA)
Greece

Articles

Clin Cases Med. 2024;4(1):CCM-04-1024 | Open Access

CAR-T Cell Therapy after Treatment with Bispecific Monoclonal Antibody: Case Report

Rey-Búa B, Alejo E, Puertas B, González-Calle V, Puig N, Gutiérrez-Gutiérrez NC, García-Sanz R and María-Victoria M

We report successful clinical experience in a patient treated with B-Cell Maturation Antigen (BCMA) Chimeric Antigen Receptor (CAR) T-cell manufactured before the treatment with a GPRC5D-bispecific monoclonal antibody. The patient was a 51-year-old man diagnosed with light chain kappa Multiple Myeloma (MM) on January 2018. After 6 prior lines of treatment, including proteasome inhibitors, immune modulatory drugs, anti CD38 monoclonal antibodies, ... Read more

CASE REPORT Updated Apr 04, 2024   PDF

Clin Cases Med. 2024;4(1):CCM-04-1023 | Open Access

Cardiac Tamponade and Pericardial Effusion in a Patient with Stage 3 Malignant Melanoma Treated with Pembrolizumab-A Case Report

Daniel Ubokudum , Ovie Okorare and Unwam Jumbo

The emergence of immunotherapy has improved the treatment of cancer. One of such agents is Pembrolizumab, a humanized antibody which acts as an immune checkpoint inhibitor, used in the treatment of melanoma and non-small cell lung cancer. We discuss a rare case of pericardial effusion due to pembrolizumab. A 75-year-old male with stage 3 malignant melanoma, presented with dyspnea after receiving ... Read more

CASE REPORT Updated Jan 12, 2024   PDF

Clin Cases Med. 2023;4(1):CCM-04-1022 | Open Access

Identification of Novel PRKAG3 Isoform in Indian Glioma Patient Samples

Megha Chaudhary, Gargi Nandi, Naveen Soni, Nargis, Sushmita Jha, Kunzang Chosdol, Rajdeep Chowdhury and Bhawana Bissa

Aim: Alternative splicing in cancer can be attributed to several factors. Cancer cells undergo extensive molecular and genetic changes, leading to dysregulation of splicing machinery and aberrant splicing patterns. It's important to note that the exact mechanisms driving increased alternative splicing in cancer are still being actively researched, and the landscape of splicing changes can vary across different cancer ... Read more

RESEARCH ARTICLE Updated Jan 06, 2023   PDF

Clin Cases Med. 2023;3(1):CCM-03-1021 | Open Access

Adult-Onset Mitochondrial Myopathies with Dyspnea as the Main Manifestation: A Case Report and Literature Review

Yongxun Zhuansun, Zizhang Yin, Jing Li, Yumo Du, Rui Chen, Lin Lin and Jianguo Li

Background: The mitochondrial myopathies are inherited metabolic diseases caused by disorders of oxidative phosphorylation at the mitochondrial respiratory chain level. The phenotype of mitochondrial myopathies is heterogeneous. Methods: Here, we report a case of a patient who presented with exertional dyspnea and sought medical consultation at respiratory department. We also review the characteristics of the patients published previously. Results: A ... Read more

RESEARCH ARTICLE Updated May 10, 2023   PDF

Clin Cases Med. 2023;3(1):CCM-03-1020 | Open Access

Wilkie Syndrome, Changing Perspectives in Image Visualization

Ronchi Brunela , Peña Gustavo and Eede Gabriela

The superior mesenteric artery syndrome is an uncommon entity included in the spectrum of vascular syndromes. The low presentation, variety of unspecific symptoms and shortage of bibliography presents a challenging diagnosis for both clinicians and radiologists. Our aim is to present a 63 years-old male patient with pancreatitis history and repeated symptoms. Further investigation with contrast-enhanced upper abdominal computed tomography revealed ... Read more

CASE REPORT Updated Feb 10, 2023   PDF