Am J Gastroenterol Hepatol. 2024;5(1):AJGH-05-1025 | Open Access
Evaristus S Chukwudike, Akwi W Asombang, Joao Filipe G Monteiro , Kelsey Sawyer , Erick Argueta , Nkengeh N Tazinkeng, Ganiyat K Oyeleke, Stella-Maris C Egboh, Avis A Nowbuth and Steven F Moss
Background: Nigeria has the highest global Helicobacter pylori infection prevalence rate. The increasing resistance of H. pylori to antibiotic treatment with concomitant increasing eradication failure is a growing global concern. We aimed to evaluate Nigeria's H. pylori eradication rates and antibiotic resistance patterns.
Methods: We systematically searched PubMed, EMBASE, Global Index Medicus, Africa-Wide Information, and ... Read more
RESEARCH ARTICLE Updated Jan 16, 2024 PDF
Am J Gastroenterol Hepatol. 2023;4(1):AJGH-04-1024 | Open Access
José Angel Marañón, Javier Nañez-Valdivieso , Vanesa Torrecillas-Mosquero , Alejandra Hernández-Bueno , Ismael Arce-Aix , Eva Navarro- Sáez, Patricia Moreno and Cristina Lozano
Background: Constipation is one of the most common functional gastrointestinal disorders in the general population, with a significant impact in the quality of life. It has been demonstrated that oxidative stress is involved in the etiopathogenesis of constipation. Furthermore, constipation can lead to oxidative injury, creating a ‘vicious cycle’. A study on MALLOLAX®, a botanical ... Read more
RESEARCH ARTICLE Updated Dec 19, 2023 PDF
Am J Gastroenterol Hepatol. 2023;4(1):AJGH-04-1023 | Open Access
Campos VENL, Neto CBC , Pinto LCA , Hahn GD, Almeida ED, Koppe DC and Stifft J
Inflammatory Bowel Disease (IBD) can have Extraintestinal Manifestations (EIM). Rarely, extraintestinal cardiac manifestations, such as Acute Pericarditis (AP), may occur. We report a case of a 19-year-old male patient with IBD, who was diagnosed with AP, confirmed by cardiac magnetic resonance. The final diagnosis was AP as an EIM of IBD. AP usually occurs following viral infections and, in IBD ... Read more
CASE REPORT Updated Oct 30, 2023 PDF
Am J Gastroenterol Hepatol. 2023;4(1):AJGH-04-1022 | Open Access
Aujla PS, Khanna R, and Konijeti GG
We report a case of gastric signet ring cell carcinoma with metastasis to the lymph nodes, peritoneum, spine, and rare spread to the colon. The diagnosis was made on pathologic examination from endoscopic and colonoscopic biopsies. Potential mechanisms include lymphatic spread, hematogenous spread and direct gastrointestinal lumen implantation.
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CASE REPORT Updated May 10, 2023 PDF
Am J Gastroenterol Hepatol. 2023;4(1):AJGH-04-1021 | Open Access
Modi K, Haq S, Saltarelli K and Mantry P
Herpes Simplex Virus (HSV) is a rare etiology of Acute Liver Failure (ALF) especially in immunocompetent patients. Here, we describe the case of a 44-year-old immunocompetent male who was admitted for ALF due to HSV hepatitis. Intravenous acyclovir was initiated prior to PCR HSV confirmation due to a recent history of an unprotected sexual encounter. The patient’s liver ... Read more
CASE REPORT Updated Mar 06, 2023 PDF
Am J Gastroenterol Hepatol. 2023;4(1):AJGH-04-1020 | Open Access
Mehmet Kürşad Keskin, Fatih Eren, Tufan Teker, Selcan Cesur, Macit Gülten and Halis Akalın
HSV hepatitis is a rare cause of acute liver failure, accounting for 0.8% of all cases and only 2% of all viral hepatitis. It is mostly seen in immunocompromised individuals and pregnant women in the third trimester following orogenital HSV-1 or HSV-2 infection, but previous reports have shown up to 25% of cases in immunocompetent individuals. Due to the lack of specific clinical ... Read more
CASE REPORT Updated Jan 06, 2023 PDF
Am J Gastroenterol Hepatol. 2023;4(1):AJGH-04-1019 | Open Access
Sonia Arnal García
The aim is to evaluate whether early extubation influences short- and medium-term postoperative morbidity and mortality.
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SHORT COMMUNICATION Updated Jan 23, 2023 PDF
Am J Gastroenterol Hepatol. 2022;3(1):AJGH-03-1018 | Open Access
Huy Quang Duong
Background: Upper gastrointestinal hemorrage due to acute esophageal varices bleeding is a common complication and a leading cause of death in patients with cirrhosis. Therefore, predicting the risk to have an active management to prevent re-bleeding and death is crucial. Currently, there are many prognostic scoring systems have been proposed, but research is needed to find a valid ... Read more
RESEARCH ARTICLE Updated Dec 22, 2022 PDF
Am J Gastroenterol Hepatol. 2022;3(1):AJGH-03-1017 | Open Access
Waleed M Alhuzaim and Nada Abouelnaga Mohamed Mahmoud
The gastro-oesophageal junction lies at the level of the diaphragm in a paraesophageal hernia, and a piece of the stomach pushes into the chest region next to the oesophagus. It is rare and often presents with no symptoms. Pain and difficulty swallowing are felt when the hernia is significant, as in our case, or strangles the stomach. A 34-year-old male ... Read more
CASE REPORT Updated Nov 30, 2022 PDF
Am J Gastroenterol Hepatol. 2022;3(1):AJGH-03-1016 | Open Access
Waleed M Alhuzaimand Nada Abouelnaga Mohamed Mahmoud
Although upper endoscopy complications like jaw dislocation are extremely rare. A 45-year-old woman underwent upper endoscopy to evaluate her significant weight loss, epigastric pain and persistent IDA. Immediately after the procedure, Jaw dislocation developed with immediate transfer to the ER and management. This report also reviews and discusses this complication.
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CASE REPORT Updated Nov 30, 2022 PDF
Am J Gastroenterol Hepatol. 2022;3(1):AJGH-03-1014 | Open Access
Wei-Feng Huang, Yi Ding, Wei Liu
A 41-year-old man presented with mild and fitful abdominal pain which had progressed over the preceding 2weeks. His past medical history was normal. The physical examination was unremarkable during acute episodes. Complete blood count, electrolytes, immunoglobulins, and liver function tests were normal. Auto antibodies tested, viral detection, and neoplastic markers were negative. Abdominal Computed Tomography (CT) scanning was performed to ... Read more
IMAGE ARTICLE Updated Jan 11, 2022 PDF
Am J Gastroenterol Hepatol. 2022;3(1):AJGH-03-1013 | Open Access
Silvia Karina Astudillo Gómez, Mauro Eduardo Ramírez Solís, Angelica Ixtaccihuatl Hernández Guerrero and Aguilar-Soto Mercedes
Positron emission tomography allows detection of benign and malignant conditions that require further investigation with other diagnostic modalities such as colonoscopy in case the metabolic activity is in the colon or rectum.
Objective: To correlate the incidental up take of 18-FDG in the colon by PET-CT with the lesions detected by colonoscopy and their histopathological outcome.
Materials ... Read more
RESEARCH ARTICLE Updated Jan 11, 2022 PDF
Am J Gastroenterol Hepatol. 2021;2(1):AJGH-02-1012 | Open Access
Bassam A Ayoub, Behairy S Behairy, Mohsen H Hussen1, Ahmed El Shaaraw, Tahany A Salem and Mohammed A Khedr
Background/objectives: Follistatin (FST) and Activin A have been described as major regulators of liver pathology and hepatocyte regeneration. FST bind with high affinity to Activin A and this complex formation block the Activin signaling. The aim of the study was to evaluate the value of plasma FST/Serum Activin A (F/A) ratio in predicting the outcome ... Read more
RESEARCH ARTICLE Updated Dec 20, 2021 PDF
Am J Gastroenterol Hepatol. 2021;2(1):AJGH-02-1011 | Open Access
Diego Armando Barraza Ortiz*, Mauro Eduardo Ramírez Solís, José Guillermo de la Mora Levy and Angelica Ixtaccihuatl Hernández Guerrero
Introduction: Endoscopic surveillance of patients with colon polyps differs depending if they are <10 mm or ≥ 10 mm, those last one with closer endoscopic surveillance. Sometimes we base subjective endoscopic estimates; an endoscopic overestimation of the size of the polyps has been demonstrated up to 50% when compared with the measurement by pathology.
Objective: To establish the ... Read more
RESEARCH ARTICLE Updated Nov 11, 2021 PDF
Am J Gastroenterol Hepatol. 2021;2(1):AJGH-02-1009 | Open Access
Cremone Cristiano, Serhal Ali, Laurent Alexis, Duvoux Christophe, Mesli Farida, Luciani Alain and Sobhani Iradj
Introduction: The diagnostic and therapeutic management of Anastomotic Biliary Stricture (ABS) is controversial. Biliary stenosis after liver transplantation requires endoscopy or surgical therapies. Endoscopic Retrograde Cholangiopancreatography (ERCP) remains a key examination for diagnosing ABS, and therapeutic strategy. However, this is an invasive investigation with potential undesirable effects. This study sought to evaluate the relevance of Magnetic Resonance Cholangiopancreatography (... Read more
RESEARCH ARTICLE Updated Oct 12, 2021 PDF
Am J Gastroenterol Hepatol. 2021;2(1):AJGH-02-1008 | Open Access
Kevin V Houston, Byung-Soo Yoo, Steve M D’Souza, James Lau, Alsiddig Elmahdi, Parth J Parekh and David Johnson
Post-COVID-19 Gastrointestinal (GI) disease management remains a clinical challenge as the medical literature continues to evolve and expand. Reports of excess GI disease burden across the population, as well as prescribed use of pharmaceuticals for symptom relief, have proven “long-haul” GI disease is prevalent across the population. This article will help to summarize the current medical literature as ... Read more
REVIEW ARTICLE Updated Aug 20, 2021 PDF
Am J Gastroenterol Hepatol. 2020;1(2):ajgh-01-1007 | Open Access
Catherine Senez
In pediatrics, since 1970, tube feeding has been a huge step forward by improving the survival of neonates exhibiting malformations or medical problems. After medical or surgical repair, resumption of oral feeding is difficult if not impossible for some. They become dependent on the tube even when it is no longer useful. Furthermore, upon returning home, continued tube feeding leads to ... Read more
REVIEW ARTICLE Updated Nov 27, 2020 PDF
Am J Gastroenterol Hepatol. 2020;1(1):AJGH-01-1006 | Open Access
Lucas Schulte, Annika Beck, Johannes Hofelich, Hanna-Sophie Reuther and Jochen Klaus
Background: Crohn’s Disease (CD) is a chronic inflammatory bowel disease with strong impact on morbidity and quality of life. Ustekinumab (UST) has been shown to be an efficient agent for bionaive and patients with treatment failure of anti-TNF-alpha drugs in randomized controlled trials, but real-life efficacy and safety has still to be evaluated. Furthermore, due to ... Read more
RESEARCH ARTICLE Updated Oct 09, 2020 PDF
Am J Gastroenterol Hepatol. 2020;1(1):AJGH-01-1005 | Open Access
Son TN* and Hoan VX
Purpose: To investigate the feasibility, safety and efficacy of Laparoscopic Surgery (LS) in management of Intestinal Duplication Cyst (IDC) in children.
Methods: Medical records of all patients with diagnosis IDC undergoing LS at our center from March, 2009 to October, 2012 were reviewed. Two types of laparoscopic procedures were performed: Completely Laparoscopic (CL) when the entire operation ... Read more
RESEARCH ARTICLE Updated May 05, 2020 PDF
Am J Gastroenterol Hepatol. 2020;1(1):AJGH-01-1004 | Open Access
Wael M Abd El Ghany, ReemYehia and Hala I Mohamed
Background: Chronic HCV in whom prior DAA treatment had failed, outcomes after retreatment are optimal. Combination of SOF, DCV, SIM, and Ribavirin in treatment experienced patients, as recommended in current guidelines despite scarce data.
Aim: To determine the efficacy and safety of SOF, DCV, SIM plus RBV in Egyptian patients infected with chronic HCV GT4 ... Read more
RESEARCH ARTICLE Updated Feb 22, 2020 PDF
Am J Gastroenterol Hepatol. 2019;1(1):AJGH-01-1003 | Open Access
Hilary Denis Solomons*
The following chronic infections can all cause Budd-Chiari Syndrome
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LETTER TO EDITOR Updated May 17, 2019 PDF
Am J Gastroenterol Hepatol. 2019;1(1):AJGH-01-1002 | Open Access
Hilary Denis Solomons*
Alcohol abuse is an important public health problem. This condition is usually identified on the basis of clinical judgement, alcoholism related questionnaires and laboratory tests, i.e., Gamma- Glutamyl Transferase (GGT), Aspartate Aminotransferase (AST) or Mean Cell Volume (MCV).
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LETTER TO EDITOR Updated May 13, 2019 PDF
Am J Gastroenterol Hepatol. 2019;1(1):AJGH-01-1001 | Open Access
Toru Ishikawa*, Marina Okoshi, Kei Tomiyoshi, Yuichi Kojima, Ryoko Horigome, Michitaka Imai, Yujiro Nozawa, Akito Iwanaga, Tomoe Sano, Terasu Honma and Toshiaki Yoshida
Aim: Lusutrombopag is a low-molecular-weight thrombopoietin receptor agonist used in clinical settings to temporarily increase platelet levels; however, predictive factors indicating its efficacy for this purpose have not yet been established. Immature platelet fractions (IPFs) reflect the productive capacity of platelets in the bone marrow and are associated with megakaryocyte levels. We determined whether an IPF change is ... Read more
RESEARCH ARTICLE Updated May 08, 2019 PDF