Gynecologist. 2021;3(1):Gynec-1020 | Open Access
Motoki Takenaka, Tatsuro Furui, Noriko Suzuki, Tiger Koike, Hitomi Aoki and Ken-ichirou Morishige
Aim: It is necessary to find a new prognostic biomarker and therapeutic strategy to improve the prognosis of ovarian cancer as the most lethal gynecologic cancer. Glutathione (GSH) is an antioxidant that protects cells against Reactive Oxygen Species (ROS). We aimed to investigate the clinical significance of GSH and effects of an inhibitor of GSH synthesis, erastin, in ... Read more
RESEARCH ARTICLE Updated Dec 08, 2021 PDF
Gynecologist. 2021;3(1):GYNEC-1019 | Open Access
Deshpande Hemant, Shinde Madhukar, Chaudhari Bhushan, Sharma Shruti and Das Alisha
Background: Today, Caesarean sections have become one of the most commonly performed surgical procedures due largely to an increase in pregnant mothers demanding pain free procedures and also partially to better imaging techniques which minimize the risks of vaginal deliveries but unfortunately, even these procedures are not totally immune to maternal and fetal morbidity or mortality. Keeping in ... Read more
RESEARCH ARTICLE Updated Jan 20, 2021 PDF
Gynecologist. 2021;3(1):GYNEC-1018 | Open Access
Deshpande Hemant, Shinde Madhukar, Reyaz Afifa, Madkar Chandrakant and Sarkar Monalisa
Background: Caesarean section is defined as the birth of foetus through abdominal and uterine incision after the period of viability. As medical science has evolved there has been an increase in the rate of caesarean section globally and thus there is a need for a better understanding of the indications and outcomes of it.
Aims and objectives:Read more
RESEARCH ARTICLE Updated Jan 15, 2021 PDF
Gynecologist. 2021;3(1):Gynec-1017 | Open Access
Jihad Al Hassan, Mayssaloun Khairallah, Kariman Ghazal, Zaynab Haroun and Eva Koulaymi
Uterine leiomyomas, also known as myomas or fibroids, are by far the commonest benign uterine tumours. It is the most common uterine neoplasm they are usually diagnosed on physical examination. Myomas and fibromyomas are not uncommon in the round, ovarian and broad ligaments, they are found in association with similar uterine tumours and their pathology and complications are the same ... Read more
CASE REPORT Updated Jan 04, 2021 PDF
Gynecologist. 2020;2(1):GYNEC-2-1016 | Open Access
Bikram Bhardwaj, Aruna Menon and Poonam Rawal
Van Wyk Grumbach syndrome is characterized by isosexual precocious puberty, delayed bone age & raised tumor markers (CA-125, AFP, LDH) in the background of severe hypothyroidism & these symptoms completely reverse to pre-pubertal state on supplementing thyroxin. High circulating levels of TSH with pre-pubertal LH is confirmatory of Van Wyk Grumbach Syndrome. These juvenile girls usually have delayed bone age ... Read more
REVIEW ARTICLE Updated Nov 24, 2020 PDF
Gynecologist. 2020;2(1):GYNEC-2-1015 | Open Access
Hethyshi Ranganna and Payal Keswarpu
Introduction: Cervical cancer contributes to a considerable toll of deaths in the developing countries despite the availability of screening procedures. Screening forms the cornerstone for reducing the burden of cervical cancer. Improvisations in the screening procedures to further lessen the morbidity and mortality associated with cervical cancer play a vital role in reaching the goal.
Aims and ... Read more
RESEARCH ARTICLE Updated Sep 30, 2020 PDF
Gynecologist. 2020;2(1):GYNEC-2-1014 | Open Access
Bhardwaj B and Rai G
In the recent years, there has been a surge in incidence of cancers globally. Not only is the incidence of cancer, even the case fatality rate due to malignancies on the rise in last few years. Gynecological malignancies are one among the commonest malignancies affecting the life of women worldwide. Ovarian cancer is the seventh most common cancer of the ... Read more
RESEARCH ARTICLE Updated Aug 12, 2020 PDF
Gynecologist. 2020;2(1):GYNEC-2-1013 | Open Access
Sofoudis Chrisostomos, Vasileiadou Dimitra, Apessou Dimitra, Avgoustinaki Maria and Koumplis Miltiadis
Aim: The aim of this study is to present a rare case of Single Organ Vasculitis (SOV) of the uterine corpus.
Case presentation: We present a 50-year-old patient who underwent TAH/BSO (Transvaginal Abdominal Hysterectomy/Bilateral Salpigoopherectomy) for a known uterine leiomyoma which had recently increased in size. Histology report described an incidental finding of vasculitis ... Read more
CASE REPORT Updated Apr 28, 2020 PDF
Gynecologist. 2020;2(1):GYNEC-2-1012 | Open Access
Vassiliadis S and Vlachos A
Hundreds of articles have unsuccessfully attempted to delineate the effect of the sunlight-induced vitamin D (vitD) on endometriosis, endometriosis-born pain and/or infertility. Numerous studies have failed to conclude in a positive or negative way on the role of vitD in this inflammatory disease that has a quite rich etiology ranging from environmental to immunologic and from infectious to gene-promoted ... Read more
REVIEW ARTICLE Updated Mar 31, 2020 PDF
Gynecologist. 2019;1(3):GYNEC-01-1011 | Open Access
Inegbenebor U
Fetal macrosomia commonly makes vaginal delivery hazardous to mothers and their babies. Furthermore it often increases the rate of obstetric intervention and cost of child birth. In addition, it poses a lifelong morbidity due to obesity, hyperlipidemia, diabetes mellitus, hypertension and coronary artery disease to affected babies and may also predispose to a vicious cycle of pre-gravid obesity and macrosomic ... Read more
REVIEW ARTICLE Updated Dec 18, 2019 PDF
Gynecologist. 2019;1(2):GYNEC-01-1010 | Open Access
Marouen Nedia, Turky Elyes, Chaari Sidik, and Fatnassi Ridha
Ovarian pregnancy is rare, with an estimated incidence of 1/7000 pregnancies. The usual risk factors and etiopathogenic mechanisms of this condition remain unknown. The exact criteria for diagnosis were established by SPIEGELBERG more than a century ago. Diagnosis of ovarian pregnancy remains difficult because of insufficient clinical and ultrasonographic findings. Nevertheless, early diagnosis of ectopic pregnancies, including ovarian localization, greatly benefited ... Read more
CASE REPORT Updated Nov 30, 2019 PDF
Gynecologist. 2019;1(2):GYNEC-01-1009 | Open Access
Hakim H, Yaich R, Halouani S, Jouou S, Arfaoui R and Rachdi R
Ectopic Pregnancy (EP) is the implantation of the fertilized egg outside the uterine cavity. In normal pregnancies, the egg fertilization occurs in the ampulla of the fallopian tube. The fertilized egg then travels to the uterine cavity where the implantation occurs. During this journey, the implantation can occur outside the uterine cavity, frequently in the fallopian tube (mostly the ampulla)
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SHORT COMMUNICATION Updated Sep 06, 2019 PDF
Gynecologist. 2019;1(2):GYNEC-01-1008 | Open Access
Kulvinder Kochar Kaur, Gautam Allahbadia and Mandeep Singh
One of the commonest causes of anovulatory infertility is PCOS in reproductive aged women. Clomiphene Citrate (CC) is one of the most commonly used drugs for achieving ovulation induction, followed by pregnancy in women having PCOS. Its mechanism of action is that it is a selective estrogen (E2) receptor modulator which it does by competitive binding nuclear E2 receptors.
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SHORT COMMUNICATION Updated Aug 02, 2019 PDF
Gynecologist. 2019;1(2):GYNEC-01-1007 | Open Access
Marouen Nedia, Turki Elyes, Khouildi Ghada and Fatnassi Ridha
Morris syndrome or Complete Androgen Insensitivity Syndrome (CAIS) is a rare genetic disorder characterized by androgen resistance. It associated the coexistence in the same subject of a male karyotype (46, XY), with male gonads, and a normal female morphology. Patients with CAIS are phenotypically females, with male gonads, but their genetic composition is that of make karyotype 46, XY. CAIS, formerly called ... Read more
CASE REPORT Updated Jul 19, 2019 PDF
Gynecologist. 2019;1(2):GYNEC-01-1006 | Open Access
Tamrakar SR, Shrestha A and Twayana K
Myoma are the common gynecological problem, mostly occur in body of uterus, cervix and broad ligament. But vaginal leiomyoma remain a rare entity with only few hundred cases reported yet. This parous lady clinically presented like Gartner’s cyst initially. The mass was excised after proper evaluation. But surprisingly, the histopathological report of excisional specimen was consistent with leiomyoma. ... Read more
CASE REPORT Updated Jul 15, 2019 PDF
Gynecologist. 2019;1(1):GYNEC-01-1005 | Open Access
Victor Manuel Vargas Hernandez
Background: Microbes inhabit all the sites of the human body and play an important role in health; The normal vaginal microbiota is composed mainly of Lactobacillus, and these have a role in the carcinogenesis of cervical cancer (both protective and harmful), for the acquisition or persistence of infection by human papillomavirus and subsequent development of cervical precursors and ... Read more
REVIEW ARTICLE Updated Jul 15, 2019 PDF
Gynecologist. 2019;1(1):GYNEC-01-1004 | Open Access
Ricardo Bassil Lasmar1 and Bernardo Portugal Lasmar2
The Office Hysteroscopy (OH) is important procedure to make diagnosis and sometimes, treatment, of intrauterine pathology, without getting the patient to Operating Room (OR). Its advantages are very well known: less cost, fast diagnosis, see and treat and several others. It’s mainly difficulty is the discomfort during the procedure. To stimule to grow the number of gynecologist to ... Read more
CASE REPORT Updated Jun 14, 2019 PDF
Gynecologist. 2018;1(1):GYNEC-01-1003 | Open Access
Nguyen Minh Thu
Sexually Transmitted Diseases (STDs) are now the commonest group of infectious diseases in most countries, particularly in the 15-50 age groups. The worldwide incidence of major bacterial and viral STDs is estimated at over 125 million cases each year. STDs not only have a negative impact on health, especially reproductive health but also seriously affect socio-economic.
Nowadays, exponential development of ... Read more
RESEARCH ARTICLE Updated Sep 14, 2018 PDF
Gynecologist. 2018;1(1):GYNEC-01-1002 | Open Access
Nguyen Thi Trang
Background: This is a review from 2 studies that determine the concentration of seminal fructose and show the correlations between seminal fructose concentration with sperm concentration, vitality and motility (progressive). Besides, these studies also show the reason of man infertility cases which azoospermia and no seminal fructose.
Materials and methods: Include random 60 normozoospermia, 60 oligozoospermia semen. Determine ... Read more
RESEARCH ARTICLE Updated Sep 14, 2018 PDF
Gynecologist. 2018;1(1):GYNEC-01-1001 | Open Access
Trieu Tien Sang, Nguyen Thanh Tung, Nguyen Thi Thanh Nga, Ngo Truong Giang, Nguyen Thi Viet Ha, Tran Van Khoa and Nguyen Thi Trang
Introduction: Spinal Muscular Atrophy (SMA) is a severe neurodegenerative autosomal recessive disorder. Most of patients are caused by the homozygous absence of a region of exon 7 and exon 8 of the telomeric copy of the SMN gene on chromosome 5. Setting up a molecular diagnostic protocol for detecting SMNt mutation in single cell is basic to Preimplantation Genetic Diagnosis.
<... Read more
SHORT COMMUNICATION Updated Sep 14, 2018 PDF