Ann Clin Pharmacol Toxicol. 2022;3(1):ACPT-1024 | Open Access
Kumari A
Viruses have full potential to cause danger to human life and once the virus infects a cell, it tries to take over its host completely. Every animate thing from plants, animals and small bacterium are infected from virus.
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EDITORIAL Updated Mar 25, 2022 PDF
Ann Clin Pharmacol Toxicol. 2022;3(1):ACPT-1023 | Open Access
Ghantasala VBR, Nalini M, Raghavullu BV, Annapurna A and Venkateswarlu M
Aim: The study was aimed to evaluate the cerebroprotective activity of hydroalcoholic extract of Talinum triangulare leaves against cerebral ischemia/reperfusion induced oxidative stress in wistar rats.
Methods: Adult Wistar rats were anesthetized with thiopentone and subjected to global cerebral ischemia by occlusion of unilateral common carotid artery for 30 minutes followed by reperfusion. Neurobehavioral parameters, Infarct ... Read more
RESEARCH ARTICLE Updated Mar 15, 2022 PDF
Ann Clin Pharmacol Toxicol. 2022;3(1):ACPT-1022 | Open Access
Ghantasala VBR, Nalini M, Raghavullu BV, Annapurna A and Venkateswarlu M
Background: Neuroprotection is one of considerable interest in search of novel therapies to improve ischemic brain damage in the present scenario. The objective of the present investigation is to study the actions of Talinum triangulare in cerebral ischemia/reperfusion induced oxidative stress in Wistar rats and in-vitro anti-oxidant actions.
Methods: Four different groups of adult Wistar ... Read more
RESEARCH ARTICLE Updated Mar 15, 2022 PDF
Ann Clin Pharmacol Toxicol. 2022;3(1):ACPT-1021 | Open Access
Amit Kumar and Govind Yadav
Immunomodulation is basically a process that can alter the immune system of an organism by interfering with its functions. The current approach is to know about the medicinal plants that are biologically active and could potentially be of help in the development of modern and new immunomodulating agents. As in modern-day life, extensive exposure to industry-based pollutants/xenobiotics has resulted ... Read more
REVIEW ARTICLE Updated Mar 03, 2022 PDF
Ann Clin Pharmacol Toxicol. 2021;2(2):ACPT-1020 | Open Access
Elshimaa Mohmed Eid
Novel compounds prepared by one-pot, multicomponent hantzsch reaction of 1, 1'-(butane-1,4-diyl)bis(indoline-2,3-dione), aromatic aldehydes and ammonium acetate, in presence of ethanol/nano Au-zeolite catalyst under mild condition. This research study the effect of novel synthesised 1,3-bis(2-arylimidazo[4,5-b] indol-4(3H)-yl)propane derivatives against COVID-19 main protease. Molecular docking simulation study was done using PDB:ID (7BUY) ... Read more
REVIEW ARTICLE Updated Nov 02, 2021 PDF
