International, Peer Reviewed, Open Access Journal

Journal of Clinical Pharmacology and Therapeutics
(ISSN: 2766-8347)

Submit Manuscript

Journal of Clinical Pharmacology and Therapeutics

Journal of Clinical Pharmacology and Therapeutics is an open access peer reviewed journal which provides latest updates in treatments, advanced procedures, technologies associated within the field of Pharmacology and other related sub-divisions.

Journal Features

Open Access

All the articles will be published under Open Access model.

Peer Review

Our editorial team performs strict peer-review process.

Publication Ethics

The journal follows standard guidelines to maintain transparency.

Submit Manuscript

The journal accepts all original articles, reviews and more.

About the Journal

Journal of Clinical Pharmacology and Therapeutics provide reports on optimal clinical use of various drugs and effects in treatment of patients.

Open Access - Journal of Clinical Pharmacology and Therapeutics

Editorial Board

Sana Irfan Khan - Journal of Clinical Pharmacology and Therapeutics

Sana Irfan Khan

Volunteering as a peer reviewer for submitted manuscripts
United States

ÖMER ALKAN - Journal of Clinical Pharmacology and Therapeutics

ÖMER ALKAN

Associate professor in the department of econometrics
Turkey

Bruno Trimarco - Journal of Clinical Pharmacology and Therapeutics

Bruno Trimarco

Federico II University of Naples (www.unina.it)
Federico II University of Naples, Director of Division of Cardiology, Coronary care unit and Cat Lab Business or sector Medical

Italy

Athanasia Papazafiropoulou - Journal of Clinical Pharmacology and Therapeutics

Athanasia Papazafiropoulou

General Hospital of Piraeus “Tzaneio”, 1st Department of Internal Medicine
Greece

Articles

J Clin Pharmacol Ther. 2022;3(1):JCPT-03-1028 | Open Access

Novel Gene Therapies Technology for Spinal Cord Injury (SCI) Therapy: Efficient Direct Lineage Reprogramming

Chunggoo Kim, Hyun Soo Shim, Yujung Chang, Hyeonjoo Im and Junsang Yoo

What is known and objectives: Spinal Cord Injury (SCI) is defined for the last few decades as patients getting wheelchair bound and under medication for a lifetime [1]. Medical battery for SCI is very limited which often results in heightened frustration for the caregivers who land up with no solid solution to the condition. However, in recent times due to the ... Read more

REVIEW ARTICLE Updated Oct 03, 2022   PDF

J Clin Pharmacol Ther. 2022;3(1):JCPT-03-1027 | Open Access

Methylphenidate Elicits Long Term Sex Difference Effects

Victor T Wilcox, Sarah D George, Pamela B Yang, Cruz Reyes-Vazquez and Nachum Dafny

Methylphenidate (MPD) is a psychostimulant widely used to treat ADHD. MPD consumption has increased among ordinary people as a cognitive enhancer and recreational drug across multiple age groups. Due to the close pharmacological profile it shares with cocaine and amphetamines there is concern that MPD has the potential to elicit dependence and abuse. The object of this study was to ... Read more

RESEARCH ARTICLE Updated Sep 14, 2022   PDF

J Clin Pharmacol Ther. 2022;3(1):JCPT-03-1026 | Open Access

The Serotonergic Signaling and the Dorsal Raphe (DR) Neurons in Adolescent Rats are the Most Engaging in Response to Acute and Chronic Methylphenidate as Compared to Other Neuronal Activities Recorded from Other Five Brain Areas

Dafny N, Reyes-Vasquez C and Liu Y

Methylphenidate (MPD) is a CNS stimulant known for its treating behavioral disorders. The increase in its use among “normal” individuals for cognitive enhancement and recreation has become a serious public health problem. This study reveals that acute MPD exposure elicits mainly increases in neuronal and behavioral activity in dose response characteristics. Chronic exposure of MPD compared to acute (0.6, 2.5 ... Read more

RESEARCH ARTICLE Updated Sep 14, 2022   PDF

J Clin Pharmacol Ther. 2022;3(1):JCPT-03-1025 | Open Access

mirna-19a-3p Promotes Malignant Progression of Breast Cancer Cells by Up Regulating PI3K-AKT-Mtor Pathway Activity Through Targeted Inhibition of PTEN

Xiaodong He, Youcheng Zhang, Chao Niu, Xiaogang Li, Bo Li and Ruofei Sun

Breast cancer is one of the leading causes of cancer-related mortality worldwide and is the most common malignancy in women. Breast cancer is not only highly prevalent and aggressive, but also highly susceptible to recurrence and metastasis, which greatly restricts its clinical treatment outcome. In recent years, miRNAs have been shown to be closely related to the recurrence and metastasis ... Read more

RESEARCH ARTICLE Updated Feb 16, 2022   PDF

J Clin Pharmacol Ther. 2022;3(1):JCPT-03-1024 | Open Access

SARS-Cov-2 and King Kong: A Similar Story

Al-kuraishy HM, Al-Gareeb AI, Hussain HN and Al-Shuely AA

King Kong is a 2005 epic monster adventure movie co-authored, produced and directed by Peter Jackson. A second edition of the 1933 movie of the same title, movie stars Naomi Watts, Jack Black, Adrien Brody. Set in 1933, the movie follows the story of an ambitious director forcing his crew to travel to the mysterious Skull Island. There, they encounter prehistoric creatures living ... Read more

LETTER TO EDITOR Updated Jan 20, 2022   PDF