J Clin Pharmacol Ther. 2022;3(1):JCPT-03-1025 | Open Access
Xiaodong He, Youcheng Zhang, Chao Niu, Xiaogang Li, Bo Li and Ruofei Sun
Breast cancer is one of the leading causes of cancer-related mortality worldwide and is the most common malignancy in women. Breast cancer is not only highly prevalent and aggressive, but also highly susceptible to recurrence and metastasis, which greatly restricts its clinical treatment outcome. In recent years, miRNAs have been shown to be closely related to the recurrence and metastasis ... Read more
RESEARCH ARTICLE Updated Feb 16, 2022 PDF
J Clin Pharmacol Ther. 2022;3(1):JCPT-03-1024 | Open Access
Al-kuraishy HM, Al-Gareeb AI, Hussain HN and Al-Shuely AA
King Kong is a 2005 epic monster adventure movie co-authored, produced and directed by Peter Jackson. A second edition of the 1933 movie of the same title, movie stars Naomi Watts, Jack Black, Adrien Brody. Set in 1933, the movie follows the story of an ambitious director forcing his crew to travel to the mysterious Skull Island. There, they encounter prehistoric creatures living ... Read more
LETTER TO EDITOR Updated Jan 20, 2022 PDF
J Clin Pharmacol Ther. 2021;2(3):JCPT-02-1023 | Open Access
Tahmina Zahan, Morshed Nasir, Abdul Quddus Shohag, Rawshan Ara perveen, Sayma Parvin and Abdul Quddus Shohag
Background: The objective was to perceive the demographic characteristics, clinical symptoms, comorbidities, and biomarkers (hematological, inflammatory, hepatic, renal, and metabolic) of Intensive Care Unit admitted survivors and deceased patients with coronavirus and link with ABO system admitted to a tertiary level hospital in Dhaka, Bangladesh. Methods: It was a retrospective cohort, conducted in Holy Family Red Crescent Medical College Hospital, ... Read more
RESEARCH ARTICLE Updated Nov 24, 2021 PDF
J Clin Pharmacol Ther. 2021;2(3):JCPT-02-1022 | Open Access
Frank Comhaire and Jan Pen
Background and objectives: Other than the direct impact of cardiopulmonary sequelae, COVID-19 disease may cause persistent signs and symptoms describes as post-COVID syndrome or long COVID. The clinical presentation and neuroimaging aspects of patients suffering from this condition are remarkably similar to those seen in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Inflammation, immune disorder and oxidative damage ... Read more
RESEARCH ARTICLE Updated Nov 10, 2021 PDF
J Clin Pharmacol Ther. 2021;2(3): JCPT-02-1021 | Open Access
Yuji Tezuka, Osamu Sekine, Akiko Hirano, Yukako Hanada, Kayo Harada, Choka Azuma, Yukako Yamamoto, Jun Ito Kobayashi, Miki Washiyama, Masanori Iwanishi, Masao Kanamori, Akira Shimatsu and Atsunori Kashiwagi
We conducted a prospective open-label, short-term, and double-arm exploratory study to investigate changes in the skin hydration state in Japanese patients with Type 2 Diabetes Mellitus (T2DM) treated with either 50 mg ipragliflozin (a Sodium-Glucose Cotransporter-2 Inhibitor: SGLT2i) (n=8) or 50 mg sitagliptin (as a control) (n=6) 1×/day for 14 days. We performed a post-hoc analysis of reported clinical data to ... Read more
SHORT COMMUNICATION Updated Oct 27, 2021 PDF