J Clin Pharmacol Ther. 2023;4(2):JCPT-04-1044 | Open Access
Namitha A, Jadav Sarma, Sumitra Debnath and Archana Hazarika
Curcumin, Eugenol, Nanocurcumin, Nanoeugenol and their combinations were known for their medicinal values especially their anti-viral effects against various viruses. Nanocurcumin and Nanoeugenol prepared by Evaporative Precipitation of Nanosuspension (EPN) and ultrasonication method had Z-average particle size of 64.22 nm and 7.270 nm, respectively which was found to be physically stable without any phase separation. The nano-ointment was prepared by the combination ... Read more
RESEARCH ARTICLE Updated May 04, 2023 PDF
J Clin Pharmacol Ther. 2023;4(2):JCPT-04-1043 | Open Access
Sumitra Debnath, Archana Hazarika and Jadav Sarma
Background: Nyctanthes arbor-tristis commonly known as Harsinghar, Night jasmine or Parijat. The present study was an attempt to evaluate the antiinflammatory activity of N. arbor-tristis leaf extract.
Method: Melonex was used as standard drug for evaluation of anti-inflammatory activity by Carrageenan induced hind paw oedema. The anti-inflammatory activity of the ethanolic, hydroethanolic, aqueous and chloroform extracts of N. arbor-tristis ... Read more
RESEARCH ARTICLE Updated May 04, 2023 PDF
J Clin Pharmacol Ther. 2023;4(2):JCPT-04-1042 | Open Access
Garcia-Molina A, Pascual-Carbonell D and Canadell-Vilarrasa L
This medical case report describes the treatment of a 59-year-old male patient with Multiple Myeloma (MM), who was admitted to the hospital with a fractured vertebra caused by an accidental fall. The patient was undergoing the VRd protocol, which consists of bortezomib, lenalidomide, and dexamethasone. Before the start of the third cycle, the patient had evidence of hyponatremia due to ... Read more
CASE REPORT Updated May 01, 2023 PDF
J Clin Pharmacol Ther. 2023;4(2):JCPT-04-1041 | Open Access
Bruna Genari, Rayara dos Santos Goncalves, Breno Dias do Vale, Roberto Carlos Abadia de Oliveira, Felipe Weidenbach Degrazia and Bruna Frizon Greggianin
Background: The term endoperiodontal lesion or endo-perio is used to describe lesions which inflammatory products are found both in the periodontium and in the pulp. Due to this endodontic and periodontal interrelation, several classifications of endo-periodontal lesion changes have been described, and for years the one that was most used were based on the disease's etiological sequence. The current &... Read more
CASE REPORT Updated Apr 28, 2023 PDF
J Clin Pharmacol Ther. 2023;4(1):JCPT-04-1040 | Open Access
Wensha Nie, Huiping Wang, Tiesong Zhang, Xia Zhang, Ou Zhang, Jiawu Yang, Shangkun Wang and Chunxia Wang
Objective: To explore the clinical characteristics and diagnosis of Glucose Transporter 1 Deficiency Syndrome (GLUT1-DS), and analyze the diagnostic significance of functional movement disorders.
Method: The clinical data of 3 children with GLUT1-DS were collected to analyze their clinical manifestations.
Results: Three cases of male patients with SLC2A1 gene mutation were included in this retrospective study. All ... Read more
RESEARCH ARTICLE Updated Apr 28, 2023 PDF