Ann Surg Edu. 2024;5(1):ASE-05-1056 | Open Access
Akam EA, Akam EY, Dhanani H, Nembhard C, Tee M and Fullum T
T he coronavirus-19 pandemic highlighted major flaws in the way healthcare is delivered globally, which invoked the need to reevaluate how healthcare systems are structured. The United States spends more money on healthcare than any other country in the world, yet the US ranks 40th in life expectancy. Factors contributing to US healthcare spending are too numerous and complex, and ... Read more
REVIEW ARTICLE Updated Dec 04, 2024 PDF
Ann Surg Edu. 2024;5(1):ASE-05-1055 | Open Access
Cheyenne Hall, Jeremy Gaskins and Sandra Kavalukas
Background: Medical education transitions from largely didactic curriculum the first two years to self-directed learning in the clinical clerkship years. A critical component of self-directed learning is bi-directional feedback to the student and the facilitator (in this case, clerkship director) to make adaptations and enhance future learning. These clinical years have proven critical to residents’ satisfaction and ... Read more
RESEARCH ARTICLE Updated Jun 05, 2024 PDF
Ann Surg Edu. 2024;5(1):ASE-05-1054 | Open Access
Deli Cui, Youman Zhang, Changjun Tan and Zhong Liu
Objectives: To investigate the effects of Chailing Decoction, an herbal medicine, on the generation of regulatory T cells (Tregs) and its potential signaling pathways in preventing graft rejection.
Methods: The study utilized C3H mice that underwent cardiac transplantation and received either Chailing Decoction or rapamycin. The survival time of the cardiac allografts, histopathological changes, the ... Read more
RESEARCH ARTICLE Updated Apr 02, 2024 PDF
Ann Surg Edu. 2024;5(1):ASE-05-1052 | Open Access
Renaat Coopman
Especially Virtual Surgical Planning (VSP) and Additive Manufacturing (AM) have become indispensable for surgical procedures. VSP allows surgeons to use Digital Imaging and Communications in Medicine (DICOM) images to virtually plan upcoming complex surgeries by using Computer Assisted Design (CAD)/ Computer Assisted Manufacturing (CAM) software. It has been shown that preoperative VSP improves surgical accuracy, leads to a faster procedure ... Read more
RESEARCH ARTICLE Updated Mar 02, 2024 PDF
Ann Surg Edu. 2024;5(1):ASE-05-1051 | Open Access
Linli Wang, Haibin Wang , Wenling Han , Chunyun Fang and Jieli Zhou
Background: Niraparib has been associated with significantly increased Progression-Free Survival (PFS) among patients with newly diagnosed and recurrent Ovarian Cancer (OC) who have had a response to platinum-based chemotherapy, regardless of BRCA status. Pre-clinical studies showed the anti-tumor mechanisms of PARP inhibitors (PARPi) and platinum have some crossover and overlap in the DNA damage repair pathway; patients who respond to ... Read more
RESEARCH ARTICLE Updated Feb 15, 2024 PDF
