Clin Cases Med. 2023;3(1):CCM-03-1021 | Open Access
Yongxun Zhuansun, Zizhang Yin, Jing Li, Yumo Du, Rui Chen, Lin Lin and Jianguo Li
Background: The mitochondrial myopathies are inherited metabolic diseases caused by disorders of oxidative phosphorylation at the mitochondrial respiratory chain level. The phenotype of mitochondrial myopathies is heterogeneous. Methods: Here, we report a case of a patient who presented with exertional dyspnea and sought medical consultation at respiratory department. We also review the characteristics of the patients published previously. Results: A ... Read more
RESEARCH ARTICLE Updated May 10, 2023 PDF
Clin Cases Med. 2023;3(1):CCM-03-1020 | Open Access
Ronchi Brunela , Peña Gustavo and Eede Gabriela
The superior mesenteric artery syndrome is an uncommon entity included in the spectrum of vascular syndromes. The low presentation, variety of unspecific symptoms and shortage of bibliography presents a challenging diagnosis for both clinicians and radiologists. Our aim is to present a 63 years-old male patient with pancreatitis history and repeated symptoms. Further investigation with contrast-enhanced upper abdominal computed tomography revealed ... Read more
CASE REPORT Updated Feb 10, 2023 PDF
Clin Cases Med. 2023;3(1):CCM-03-1019 | Open Access
Irvine B , Ayinapudi K , Farhana L , Le Jemtel TH and Johnson C
A symptomatic 48-year-old woman, distance runner, was diagnosed with a dilated cardiomyopathy and found to have a likely pathogenic Titin truncating variant gene. Symptoms and left ventricular volumes improved months after withdrawal from running. Heavy aerobic exercise may unveil Titin truncating variant induced cardiomyopathy.
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CASE REPORT Updated Feb 10, 2023 PDF
Clin Cases Med. 2023;3(1):CCM-03-1018 | Open Access
O De Marco, Diomedi FC, Vallese S , Bianchi S , Gigante A and Cianci R
We report the case of an old man with a 4-year history of Polycythemia Vera (PV) with a new proteinuria in nephrotic range. A biopsy was performed with diagnosis of Focal Segmental Glomerulosclerosis (FSGS). Glomerular proliferative or sclerotic lesions associated with proteinuria and CKD are present in patients with untreated or uncontrolled PV. This observation suggests the need for extensive ... Read more
CASE REPORT Updated Feb 10, 2023 PDF
Clin Cases Med. 2022;2(2):CCM-1016 | Open Access
Franco Pavese
Recently a study by this author has been published about critical inconsistencies affecting this extremely extended type of control in home care. It was shown that basically the tests could be false or inconclusive due to insufficient rules of normalization governing this kind of test. In particular, the meaning of the advised (marginal) use of “control solutions” is ... Read more
MINI REVIEW Updated Oct 10, 2022 PDF
Clin Cases Med. 2022;2(2):CCM-1015 | Open Access
da Silva CGL, Maria do Socorro Vieira dos Santos, Feitosa Machado SS, Barreto Tiburi RG, Pinheiro Jucá MC, Barros LL, de Carvalho AFM, Novais Lima BR, de Souza Bezerra JP and Rolim Neto ML
The mechanisms of coagulation disorder in COVID-19 are complex. However, it is already postulated that endotheliopathy and platelet activation may be important factors, causing direct damage to endothelial cells and the imbalance of inflammatory response, manifesting by venous arterial or microvascular thrombosis. The present study aims to describe a clinical case of an 8-year-old female patient with disseminated intravascular coagulation ... Read more
RESEARCH ARTICLE Updated Sep 26, 2022 PDF
Clin Cases Med. 2022;2(1):CCM-1014 | Open Access
Meliksah Taner, Tumay AK, Burhan Engin, Tugce Eskazan and Gunay Can
Background and objectives: Anti-IL17A treatment has been identified as exacerbating Inflammatory Bowel Disease (IBD) and leading to new-onset IBD, and Fecal Calprotectin (FCP) is a good marker of intestinal inflammation. This study aimed to evaluate the results of FCP screening and whether FCP level correlates with psoriasis severity before anti-IL17A treatment.
Methods: The present ... Read more
RESEARCH ARTICLE Updated Sep 09, 2022 PDF
Clin Cases Med. 2022;2(1):CCM-1013 | Open Access
Calleja MAA, Vicente PC, Montserrat MC, Andy CFB, Oscar TG, Luisa VZK, Irene SG, Rosario ML, Inmaculada BAD, Elena TDM, Lara RA, Fernando PP and Lucia GDE
In born errors of metabolism are rare and difficult to diagnose in adults, especially in those without affected relatives. We report a case of coma in a young healthy adult of unexpected origin. The presence of white matter disease, the triggering factors and metabolic derangements associated offer us the key to diagnosis.
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CASE REPORT Updated Aug 02, 2022 PDF
Clin Cases Med. 2022;2(1):CCM-1012 | Open Access
Khamdan F and Shah M
Secondary syphilis, the most vivid stage of the disease, is called “the great imitator”, as it has a variety of cutaneous manifestations that mimic other diseases. Furthermore, the systemic vasculitis caused by endothelial invasion of T pallidum in syphilis can result in a variety of systemic manifestations such as neurological, renal, and hepatic involvement. We present a case ... Read more
CASE REPORT Updated Jul 08, 2022 PDF
Clin Cases Med. 2022;2(1):CCM-1011 | Open Access
Suhas Erande
In1980s, an entity named as Nonalcoholic Fatty Liver Disease (NAFLD) or Nonalcoholic Steatohepatitis (NASH), resembled histopathologically with Alcoholic Liver Disease (ALD) [1,2]. Even then, the biochemical & clinical features of NAFLD & ALD were noted as distinct from each other. Association of NAFLD with T2DM & obesity was described in 1970 [3]. When Ludwig first used the term NASH, this association ... Read more
PERSPECTIVE Updated Jun 28, 2022 PDF
Clin Cases Med. 2022;2(1):CCM-1010 | Open Access
Saxena AK, Kumar V, Sinha L, Kumar U and Kumar S
Anorectal Malformations (ARMs) are one of the rare anomalies called “Birth Defects” associated during development of digestive system. During embryogenesis, the abnormal hindgut develops either isolated or along with other congenital abnormalities perhaps due to involvement of genetic and epigenetic factors like methylenetetrahydrofolate reductase (C677T) gene polymorphism. However, little is known about etiopathology of ARMs cases. In ... Read more
RESEARCH ARTICLE Updated Jun 28, 2022 PDF
Clin Cases Med. 2021;1(2):CCM-1009 | Open Access
Husam H Mansour
Background: Mounier-Kuhn syndrome, or tracheobronchomegaly, is a rare clinical entity characterized by abnormal dilatation of the trachea and main bronchi secondary to atrophy of the muscular and elastic tissues in the trachea and main bronchial walls. Consequently, the flaccid airways become widened during inspiration and collapse during expiration. The development of volumetric High-Resolution CT (HRCT) will contribute to ... Read more
CASE REPORT Updated Sep 18, 2021 PDF
Clin Cases Med. 2021;1(2):CCM-1008 | Open Access
Syed Hasan Ahmad
A 37-year-old male patient presented with a 3-day history of headaches followed by an episode of confusion slurring of speech and some self-resolving weakness of right arm. A CT head demonstrated a wedge-shaped infarct in left parieto-occipital region. Extensive workup to find out any cause of this infarct was unsuccessful. A neurological assessment was carried out which confirmed the likely ... Read more
CASE REPORT Updated May 18, 2021 PDF
Clin Cases Med. 2021;1(1):CCM-1007 | Open Access
David N. Ku, Ben Ku, Traci Leong and Zixiang Liu
Background: Current prevalence of COVID-19 drives many policy decisions, but is hampered by ambiguities in testing and reporting. We propose an alternative method for estimating community prevalence that is inexpensive and timely. We test the Hypothesis that the survey sampling provides a quantitative prevalence that is similar to widespread genomic or serological testing.
Methods: We have ... Read more
RESEARCH ARTICLE Updated Mar 26, 2021 PDF
Clin Cases Med. 2021;1(1):CCM-1006 | Open Access
Kapil D Jamwal
Post EVL (Endoscopic Variceal Ligation) ulcers (PEBU) are not uncommon with an incidence of 3% to 15% in various studies [1,2]. PEBU presents from 3 days to 21 days after the EVL but most commonly from 10 to 13 days. It is clinically relevant because of its association with poor outcomes and increased mortality.
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IMAGE ARTICLE Updated Feb 10, 2021 PDF
Clin Cases Med. 2021;1(1):CCM-1005 | Open Access
Madhumita Srivastava
Odontogenic infection has afflicted humankind since our civilization has been fighting across microorganism by man dates back to ancient civilization. The incidence of space infections has been greatly reduced by modern antibiotic therapy, but it can be fatal if not diagnosed on time. Analysis of clinical outcome of odontogenic infection if disregarded may lead to serious unwanted complication.
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CLINICAL VIDEO Updated Feb 25, 2021 PDF
Clin Cases Med. 2021;1(1):CCM-01-1004 | Open Access
Mauro Luisetto, Nili BA, Khaled Edbey, Mashori GR, Ahmed Yesvi Rafa and Oleg Yurevich Latishev
Aim of this work is to evaluate the chemical-physical binding between some respiratory virus and their carrier like particulate matter, water particles dust and other. This make possible to verify if a virus is airborne or not and the forces that regulate the bioaeresol containing virus. The envelope of coronavirus whit their chemical -physical properties and electrical charge are fundamental ... Read more
RESEARCH ARTICLE Updated Jan 25, 2021 PDF
Clin Cases Med. 2020;1(1):CCM-01-1003 | Open Access
Theofilidis Antonis
Introduction: Observations that the onset of epileptic seizures improved the psychotic symptomatology of some patients led to the theory of functional dependence and biological competition for schizophrenic and epileptic symptoms. A positive link between epilepsy and schizophrenia was later advocated. The current position is that there is a relationship, but in the link that appears to be epilepsy and psychosis, ... Read more
REVIEW ARTICLE Updated Oct 21, 2020 PDF
Clin Cases Med. 2020;1(1):CCM-01-1002 | Open Access
Ezgi Ersoy Yesil*, Hasan Kayabasi, Mustafa Behcet Demirbas and Dede Sit
A pandemia is threatening public health he worldwide due to novel corona virus disease which was first reported in Wuhan, China at the last days of December 2019. Clinical manifestations of SARS-CoV-2 vary among people. Patients with diabetes mellitus, hypertension and cardiovascular disease, chronic renal disease and malignancy especially have risk of developing severe disease. Kidney transplant recipients also might have ... Read more
CASE REPORT Updated Aug 03, 2020 PDF
Clin Cases Med. 2020;1(1):CCM-01-1001 | Open Access
Theofilidis Antonis, Sofologi Maria, Fountoulakis Kostas and Nimatoudis John
Craniocerebral damage due to Traumatic Brain Injury (TBI) mediated by multiple molecular cascades can be expressed through neuropsychological complications, involving cognitive deficits, post-traumatic epilepsy, personality change, as well as severe and chronic psychosis. The purpose of this study was to investigate and identify potential patterns associated with the neuropsychological manifestations following TBI by examining bibliographic case reports through a systematic ... Read more
CASE REPORT Updated Apr 10, 2020 PDF