J Pediatr Neonatol. 2024;5(1):JPN-05-1039 | Open Access
Fayize Maden Bedel, ÖzgürBalasar, RamazanKeçeci, HüseyinAltunhan and HüseyinÇaksen
We report a newborn patient who was consulted for her dysmorphic facial features. She was born at 37 gestational weeks as 2970 gr (25 p-50 p) through vaginal route. Her birth height was 50 cm (50 p) and head circumference was 33.3 cm (<3p). She cried immediately after birth but she had dyspnea and feeding difficulties that were caused by cleft palate. We examined the ... Read more
CASE REPORT Updated Mar 13, 2024 PDF
J Pediatr Neonatol. 2023;4(3):JPN-04-1038 | Open Access
Mohamed Sellouti , Anas Ayad, Rachid Abilkassem and Aomar Agadr
Background: Newborn infants with maternal-fetal ABO incompatibility face an increased risk of developing significant hyperbilirubinemia. Thiqs study aimed to investigate the clinical manifestations and outcome of treatment modalities. Methods: It was a retrospective, descriptive and analytical study conducted in the neonatal unit of Mohamed V military Hospital of RABAT. A total of 75 neonates with blood group A or B born ... Read more
RESEARCH ARTICLE Updated Oct 18, 2023 PDF
J Pediatr Neonatol. 2023;4(3):JPN-04-1037 | Open Access
Shilpa U Kalane, Lavannya Raste, Vishakha Haridas, Sampada Patwardhan and Uday P Devaskar
Objective: To investigate if Pasteurization of Mother’s Breast Milk (PMBM) prior to giving it to her baby alters the clinical course of CMV in premature neonates born with CMV in their urine. Study design: When a delivery occurred before 34 weeks of GA, maternal blood and baby’s urine were tested for the presence of CMV-IgG antibodies and ... Read more
RESEARCH ARTICLE Updated Sep 14, 2023 PDF
J Pediatr Neonatol. 2023;4(3):JPN-04-1036 | Open Access
Ummey Tamima Nasrin, Md Abdul Mannan, Sadeka Choudhury Moni, Md Kamrul Hasan Shabuj, Jahanara Perveen, Prohlad Karmaker, Shazia Afreen, KM Mahbubur Rahman, Mohammad Rasel, Shamima Akhter, Afrina Wahab, Shimul Mandal and Mohammod Shahidullah
Background: Sepsis is a major cause of neonatal mortality in developing countries. However, with current severity scores and laboratory parameters, early diagnosis and predicting outcomes of neonatal sepsis is a serious challenge. Lactic acid concentration is a readily available pragmatic means to predict outcomes of various comorbidities. However, its utility in neonates remains unexplored. Objective of the study: The objective ... Read more
RESEARCH ARTICLE Updated Sep 13, 2023 PDF
J Pediatr Neonatol. 2023;4(2):JPN-04-1035 | Open Access
Zachary Henig, Alyssa Khoo, Cole Turner, Kashif Iqubal, Kristyn Pierce, Pablo Castaneda and Erin Hanft
Objective: To evaluate the incidence of Developmental Hip Dysplasia (DDH) in preterm breech infants at our institution and screening practices among providers that manage DDH in the preterm population. Design: We reviewed charts of infants born in a single quaternary care urban medical center between 2012-2022. Infants born <37 weeks Gestation Age (GA) with breech presentation and screening ultrasonography done ... Read more
RESEARCH ARTICLE Updated Sep 04, 2023 PDF
J Pediatr Neonatol. 2023;4(2):JPN-04-1034 | Open Access
Sheikh SB* , Al-Rehaili K and Al-Harbi DL
We report a case of glucose galactose malabsorption in a patient who presented with renal failure. Our aim is to inform pediatricians about the life-threatening complications associated with glucose galactose malabsorption, especially renal complications.
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CASE REPORT Updated Aug 23, 2023 PDF
J Pediatr Neonatol. 2023;4(2):JPN-04-1033 | Open Access
Jahanara Perveen, Sonia Akter, Ummey Tamima Nasrin, KM Mahbubur Rahman, Renesa Reza, Sadeka Choudhury Moni, Sanjoy Kumer Dey, Mohammod Shahidullah and Md Abdul Mannan
Background: Neonatal sepsis is a critical condition and one of the important causes of neonatal mortality and morbidity. Late onset neonatal sepsis is an important type of neonatal sepsis. Vitamin D has important immune modulatory effects. Vitamin D deficiency is widespread among pregnant women and neonates. The association of vitamin D deficiency with neonatal sepsis has recently been an area ... Read more
RESEARCH ARTICLE Updated Aug 23, 2023 PDF
J Pediatr Neonatol. 2023;4(2):JPN-04-1032 | Open Access
Seifu Awgchew Mamo , Taye Mezgebu , Tigest Eneyew , Eliase Ezo and Zerihun Demisse
Background: Meconium Aspiration Syndrome is one of the most frequent causes of respiratory distress in newborn babies. Meconium Aspiration Syndrome (MAS) is a global health concern and a major contributing factor to morbidity and mortality among neonates, particularly in low and middle-income countries. Data on the magnitude and risk factors of Meconium Aspiration Syndrome among neonates admitted into NICU were ... Read more
RESEARCH ARTICLE Updated Jun 23, 2023 PDF
J Pediatr Neonatol. 2023;4(2):JPN-04-1031 | Open Access
Abdelrazak Mansour Ali , Radwa Abdelrazak Ali and Ahmed Abdelrazak Ali
This novel study would describe a new disease illness although it is not uncommon but never described, categorized, or paid the attention of physicians or researchers. Satan and Demons “Jinn” are created from ultrasound energy, which is the only conventional wave that produces high heat that may reach 3000 degrees. A technique that allows ultrasound to penetrate bone or ... Read more
RESEARCH ARTICLE Updated Jun 09, 2023 PDF
J Pediatr Neonatol. 2023;4(1):JPN-04-1030 | Open Access
Singh K , Rhee L, Hedriana HL, Boe NM
Nonimmune hydrops fetalis is diagnosed when two or more of the following findings are identified on prenatal ultrasound: fetal ascites, pleural effusion, pericardial effusion, skin edema or polyhydramnios. We report on a rare case of fetal hydrops resulting from hereditary hemolytic anemia in association with a novel variant in the SPTA1 gene.
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CASE REPORT Updated Jun 01, 2023 PDF
J Pediatr Neonatol. 2023;4(1):JPN-04-1029 | Open Access
Harsh Prabha Soni*, Pratima Beck and Sharja Phuljhele
Introduction: LBW is known to be associated with subsequent health issues such as poor anthropometric growth in childhood. Late catch-up growth of preterm infants throughout childhood linked to an adverse health outcome. The aim of this study is to study the growth parameters of healthy low birth weight neonates discharged from post-natal ward. Material and methods: This was a hospital ... Read more
RESEARCH ARTICLE Updated May 05, 2023 PDF
J Pediatr Neonatol. 2023;4(1):JPN-04-1028 | Open Access
Abdul Mannan MD, Shahana Akter, Ummey Tamima Nasrin, Sadeka Choudhury Moni, Sharmin Afroze, Mosammad Alpana Jahan, Mohammad Abul Khayer and Nargis Ara Begum
Background and objective: Necrotizing Enterocolitis is a common complication of prematurity, causing morbidity and mortality. There is scarcity of documentation on the safety or efficacy of routine use of probiotics. Therefore, incidence of NEC, feed intolerance, and all-cause mortality, can be decreased by using probiotic supplementation is the aim of the study. Methods: This prospective double-blinded, placebo controlled, randomized trial ... Read more
RESEARCH ARTICLE Updated May 05, 2023 PDF
J Pediatr Neonatol. 2023;4(1):JPN-04-1027 | Open Access
Mohammed El A Zayed , Sara OM Gadim and Omer Saeed Magzoub
Serum sodium concentration of ≥ 150 mmol/l in neonates is known as neonatal hypernatremia. Variable incidence of hypernatremia depending on countries regions geographic settings or socioeconomic status and it has been increasing over the past three decades. Objectives: To determine risk factors, treatment and short-Term outcome of hypernatremia in Neonates admitted to Al-Obeid Specialized Pediatric Hospital, North Kordofan State Sudan ... Read more
RESEARCH ARTICLE Updated Apr 06, 2023 PDF
J Pediatr Neonatol. 2023;4(1):JPN-04-1025 | Open Access
Heisler GHF and Barbosa ADM
Objective: To characterize the nasopharyngeal microbiota of high- and low-risk newborns in the Hospital Universitário Antônio Pedro, Universidade Federal Fluminense (HUAP-UFF) neonatal unit. Method: This prospective cross-sectional study included newborns from the Neonatal Unit of the HUAP-UFF divided into two groups: Intensive Care Units - Intermediate Unit ICU-IU (G1) and rooming-in (G2). After the newborn was ... Read more
RESEARCH ARTICLE Updated Jan 31, 2023 PDF
J Pediatr Neonatol. 2022;3(2):JPN-03-1024 | Open Access
Hadrich Z1, Saidane M1, Youssef M1, Bouzidi H2, Ghanmi S1 and Ben Hamouda H1*
Prolonged neonatal transient hyperinsulinism can occur in newborns without predisposing perinatal factors. It can present as congenital hyperinsulinism responsible for severe hypoglycemia requiring early treatment to reduce the risk of long-term neurological sequelae. We report a case of prolonged neonatal transient hyperinsulinism in a full-term infant born by spontaneous vaginal delivery, without intrauterine growth retardation, maternal diabetes, or perinatal asphyxia. ... Read more
CASE REPORT Updated Jan 01, 0001 PDF
J Pediatr Neonatol. 2022;3(2):JPN-03-1023 | Open Access
Fatma EKER1* and Serpil USTUNDAG2
Introduction: To assess the efficacy of laparoscopy in patients with non-palpable testes. To identify associated diagnoses in the studied patients, proposing a critical route of diagnosis and treatment for the patients included in the study. Methods: Qualitative, retrospective, longitudinal study. Analyzing patients with ages 0 to 18 years old with IAT operated from 2012 to 2019. They were evaluated preoperatively with clinical history, laboratory ... Read more
RESEARCH ARTICLE Updated Jan 01, 0001 PDF
J Pediatr Neonatol. 2022;3(1):JPN-03-1022 | Open Access
Fatma EKER1* and Serpil USTUNDAG2
This research was carried out quasi-experimentally for families of children with epilepsy to assess the impact of psychoeducation to parents' knowledge, anxiety for epilepsy and State-Trait Anxiety levels. The population of the investigation covers, 560 parents of children with epilepsy followed by a University Research Center of Child Neurology. The study sample constituted 68 participants including 35 test and 33 control parents. Research data, ... Read more
RESEARCH ARTICLE Updated Jan 01, 0001 PDF
J Pediatr Neonatol. 2022;3(1):JPN-03-1021 | Open Access
Antonio Santos1, Kelsey Montgomery2, David Kays3 and Tiffany Tonismae1
To review a case of novel in utero thoracoamniotic shunt placement for pleural effusion in the setting of congenital diaphragmatic hernia (CDH).
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CASE REPORT Updated Jan 01, 0001 PDF
J Pediatr Neonatol. 2022;3(1):JPN-03-1020 | Open Access
Oukhouya MA1*, Abdellaoui H2, Tazi MC2, Atarraf K2 and Afifi MA2
Type 1 neurofibromatosis (NF-1), is one of the most common human single-gene disorders, affecting at least 1 million persons throughout the world. In this report we describe an extremely rare case of big plexiform neurofibromas responsible for a large leg. X-ray showed bone thickening, CT scan showed periosteal thickening and a large fluid subperiosteal masse. The patient had an extended intra-lesional curettage ... Read more
CASE REPORT Updated Jan 01, 0001 PDF
J Pediatr Neonatol. 2022;3(1):JPN-03-1019 | Open Access
Manuel Fernández-Elías1, María López-Marcos1, María Teresa Charlo1, Elena Mellado1, Walter A Goycochea-Valdivia2, Miguel Muñoz1 and Elia S Valderrábanos1*
Mucormycosis and Aspergillosis are potentially lethal invasive fungal infections that mainly affect immunocompromised and diabetic patients, being exceptional in the paediatric population. The diagnosis is microbiological, and it is essential to have a strong clinical suspicion. The treatment is based on the combination of antifungal drugs (liposomal amphotericin B with voriconazole) and surgical debridement. Invasive fungal coinfection by Mucor and ... Read more
CASE REPORT Updated Jan 01, 0001 PDF
J Pediatr Neonatol. 2022;3(1):JPN-03-1018 | Open Access
Elsayed I Salama1-3* and Nermin M Eladawy1
Background: Endoscopic variceal sclerotherapy (EVS) is still not well defined in children with portal hypertension due to liver disease. We tried to investigate benefits and factors affecting outcome of this procedure. Methods: We conducted retrospective random study on 49 children, aged 2 to 17 years, 30 male and 19 females, presented to our unit with esophageal bleeding. Children were injected with 1% ethanolamine maleate and followed ... Read more
RESEARCH ARTICLE Updated Jan 01, 0001 PDF
J Pediatr Neonatol. 2021;2(2):JPN-02-1017 | Open Access
Milella Leonardo1*, Raimondo Pasquale2, Ficarella Maria Teresa1, Calabrese Gerolmina1, Sisto Michele1, Moliterni Paola1, Lasorella Maria Luigia1, Cito Fabiana1, Torres Diletta3, Santangelo Luisa3, Carbone Vincenza3, Piscopo Giovanni3 and Giordano Mario3
Introduction: Progressive familial intrahepatic cholestasis (PFIC) is a group of inherited disorders that result in the impairment of bile flow through the liver that predominantly affects children. Many of these patients will progress to end stage liver disease and require liver transplantation. Acute on chronic liver failure (AoCLF) may occur in these patients, with rapidly progressive evolution and severe prognosis ... Read more
CASE REPORT Updated Jan 01, 0001 PDF
J Pediatr Neonatol. 2021;2(2):JPN-02-1016 | Open Access
Michael S Schimmel
EDITORIAL Updated Jan 01, 0001 PDF
J Pediatr Neonatol. 2021;2(2):JPN-02-1015 | Open Access
Ana Paula Gularte Barbosa, Marcia Montagner Maia, Michelle Vargas Reginatto, Regina Gema Santini Costenaro, Franceliane Jobim Benedetti*
Purpose: To describe the foods contained in the school children’s lunch boxes and classify them according to their characteristics and degree of processing.
Method: This is a descriptive, cross-sectional study, conducted in private schools located in Santa Maria, Rio Grande do Sul, Brazil. The collection was carried out between 2018 and 2019, having as target public children enrolled in the ... Read more
RESEARCH ARTICLE Updated May 20, 2021 PDF
J Pediatr Neonatol. 2021;2(2):JPN-02-1014 | Open Access
AKM Mamunur Rashid*
A number of children frequently visit in our daily practice with presenting symptom of limb pain especially at night. There might be a relationship between low level vitamin-D and limb pain in children. The children presenting with nonspecific limb pain without signs of joint inflammation and other diseases visited to the private clinic are included in this study. These children ... Read more
SHORT COMMUNICATION Updated May 20, 2021 PDF
J Pediatr Neonatol. 2021;2(1):JPN-02-1013 | Open Access
Johnny Ludvigsson
Background: Screening to find individuals with high riskof developing Type 1 diabetes (T1D) is needed to recruit participants for prevention trials and studies to preserve residual beta cell function at diagnosis. Screening may also decreasethe incidence of diabetic keto-acidosis (DKA) at diagnosis. However screening may cause anxiety and decrease quality of life for patients and their relatives. The aim of ... Read more
RESEARCH ARTICLE Updated Apr 08, 2021 PDF
J Pediatr Neonatol. 2021;2(1):JPN-02-1012 | Open Access
Sisay Moges1, Dejene Ermias Mekango2* and Ayalew Astatkie3
Background: A large number of children die soon after birth. Improving the survival chances of newborns remains an urgent challenge that needs intensified commitment to achieve the Sustainable Development Goals (SDGs) target of neonatal mortality reduction. This study aimed to estimate neonatal mortality rate and identify predictors of neonatal death among neonates admitted into the neonatal intensive care unit (NICU) ... Read more
RESEARCH ARTICLE Updated Apr 08, 2021 PDF
J Pediatr Neonatol. 2021;2(1):JPN-02-1011 | Open Access
Mario Giordano*
EDITORIAL Updated Apr 03, 2021 PDF
J Pediatr Neonatol. 2021;2(1):JPN-02-1010 | Open Access
Adrià Costa-Roig*, Maria Del Peral Samaniego, Lucía Rodríguez Caraballo, José Antonio March-Villalba, Alba Polo, Mª Ángeles Conca and Agustín Serrano Durbá
Introduction: Xanthogranulomatous Pyelonephritis (XGP) is a rare infective disease involving functional failure of the affected kidney. Although its certainty diagnosis is anatomopathological, it can be suspected by imaging. Ultrasound (US) and Magnetic Resonance Imaging (MRI) have been described as diagnostic methods. Nephrectomy persists as the treatment of choice in these cases.
Aim: To describe our series of patients with PXG, ... Read more
RESEARCH ARTICLE Updated Feb 02, 2021 PDF
J Pediatr Neonatol. 2021;2(1):JPN-02-1009 | Open Access
Soumana A1,2, Samaila A1,2*, OumarouBaka M1, Kamaye M2,3, Garba M1, Mamoudou AD3, Ibrahim ML4, Djibrilla Almoustapha A2,5, Yacouba A2 andMalamAbdou B2,5
Blood transfusion involves risks that maybe life-threatening. Infectious risk is serious in Niger with the significant prevalence infections among blood donors. The objective of this study is to evaluate transfusional infectious risks in paediatric settings in two national hospitals of Niamey in Niger. This was a prospective cohort study in the paediatric ward of two national hospital of Niamey. The ... Read more
SHORT COMMUNICATION Updated Jan 27, 2021 PDF
J Pediatr Neonatol. 2021;2(1):JPN-02-1008 | Open Access
Liu Jinxiang* and Liu Chengliang
Objective: To observe the changes of testis volume before and after operation in children with bilateral cryptorchidism.
Patients and methods: Bilateral cryptorchidism in outpatient follow-up and clinical operation were selected. Doppler ultrasound was used to measure testis volume at 0-3 months of age (B1), 3-6 months of age (B2), preoperative (B3), postoperative 3 months (B4), and postoperative 6 months (B5), 12 cases in ... Read more
RESEARCH ARTICLE Updated Jan 06, 2021 PDF
J Pediatr Neonatol. 2020;1(2):JPN-01-1007 | Open Access
Coraal Cohen1*, Gonzalo Cadima1 and Daniel Castellanos2
This study retrospectively reviewed survey data that explored the mental, emotional, social, and physical well-being and coping ability of adolescents in Broward County, Florida during the COVID-19 pandemic. In May 2020, an anonymous online survey was conducted in collaboration with community partners. A convenience sample of 359 adolescents aged 12-21 years (Median = 14 years) in middle or high school—67% female, 50% Black/African ... Read more
RESEARCH ARTICLE Updated Oct 06, 2020 PDF
J Pediatr Neonatol. 2020;1(2):jpn-1006 | Open Access
Josephine Elia, Yumiko Izaki, Alexander Ambrosini and Hakon Hakonarson
Animal models, human genetic and epigenetic studies as well as imaging and functional brain studies lend support for significant glutamatergic dysfunction in ADHD. Furthermore, medications with glutamatergic functions decrease ADHD symptoms and effective ADHD medications have glutamatergic activity. Neurodevelopmental studies indicate that glutamatergic neurotransmission has widespread impact on brain development throughout gestation and after birth. This provides a wide window ... Read more
REVIEW ARTICLE Updated Jun 05, 2020 PDF
J Pediatr Neonatol. 2019;1(1):JPN-01-1005 | Open Access
Helen Kest and Lucerna Michelle
Respiratory Syncytial Virus (RSV), the top cause of Lower respiratory tract disease in young children, continues unabated as a global health problem. Clinical presentations vary depending on age, prematurity, previous infections, and other co-morbid factors. Bronchial airway tissue pathogenicity is due to the interplay between viral replication and cytotoxicity and the host inflammatory immune response. The resulting inflammation of the ... Read more
REVIEW ARTICLE Updated Mar 14, 2019 PDF
J Pediatr Neonatol. 2018;1(1):JPN-01-1004 | Open Access
Yan-Jun Wu and Ann-Ching Wang
Neonatal cerebral sinovenous thrombosis is a rare and potentially life threatening disease, leading to long term neurological deficits. The pathogenesis of cerebral sinovenous thrombosis in neonates is still unclear. Many potential risk factors have been drawn such as gestational or delivery complications, or co-morbid conditions including dehydration, sepsis or cardiac defects. Nevertheless, the clinical presentation of this disorder in newborns ... Read more
RESEARCH ARTICLE Updated Dec 19, 2018 PDF
J Pediatr Neonatol. 2018;1(1):JPN-01-1003 | Open Access
Maria A Karalexi, Marina Mitrogiorgou, Georgia Georgantzi, Eleni Kontaki, Periklis Foukas, Konstantinos Triantafyllou, Feneli Karachaliou and Smaragdi Fessatou
Celiac Disease (CD) is an autoimmune disease with a broad spectrum of clinical disorders and associated comorbidities. In many cases, patients have no gastrointestinal disorders and are referred to paediatric gastroenterologist due to combined endocrinological disorders. We aimed to identify children with CD and determine the prevalence of paediatric endocrinologists’ referrals due to positive anti-tTG antibodies and coexisting T1... Read more
RESEARCH ARTICLE Updated Sep 06, 2018 PDF
J Pediatr Neonatol. 2018;1(1):JPN-01-1002 | Open Access
Hameed NN and Talab HS
Objective: To study the neonatal morbidity and case fatality in preterm infants with respiratory distress syndrome treated with different methods of administration of surfactant replacement therapy.
Study design: This cross-sectional analytic study included 104 preterm infants, who had respiratory distress syndrome during one year period. The sample was divided into prophylactic, early and late rescue groups, ... Read more
RESEARCH ARTICLE Updated Sep 06, 2018 PDF
J Pediatr Neonatol. 2018;1(1):JPN-01-1001 | Open Access
Mohammad Kamrul Hassan Shabuj, Sanjoy Kumer Dey, Sadeka Choudhury Moni, Ismat Jahan, Mahboba Akther, Md Abdul Mannan and Mohammod Shahidullah
Bartter syndrome is a genetic rare disorder usually present with set of renal tubular disorders characterized by hypokalaemia, hypochloraemia, metabolic alkalosis, and hyper reninemia and normal blood pressure. Renal tubular abnormality of sodium, potassium and Chloride resorption results in excessive urinary losses of sodium, chloride, and potassium. We report a case of Neonatal Bartter syndrome, who presented from 48 hrs of ... Read more
CASE REPORT Updated Sep 06, 2018 PDF