World J Clin Case Rep Case Ser. 2024;4(1):WJCCRCS-04-1023 | Open Access
Luis André Salinas Agramonte, Alberto Alvarado Miranda , Fanny Porras , Liliana Patricia Torres Agredo , Juan Antonio Matus Santos , Fernando Ulises Lara Medina and Tatiana Vidaurre Rojas
Introduction: Malignant myoepithelioma of the breast is a tumor of infrequent presentation, in the literature and in published case reports is formed by polygonal cells with diffuse pattern or malignant spindle cells with myoepithelial differentiation. Sixty cases have been reported in the indexed literature; because of this scarcity of cases the knowledge of its biological behavior and ... Read more
CASE REPORT Updated Mar 16, 2024 PDF
World J Clin Case Rep Case Ser. 2024;4(1):WJCCRCS-04-1022 | Open Access
Halid Melkamu Ahmed, Aderajew Walle Belete, Fikadu Negash, Biniyam Yohannes, Bikilla Regassa, Hilmneh Yirdaw and Muhammed Tuha
Introduction: The wrapping of the ileum around the sigmoid colon and its mesentery, or vice versa, is known as Ileosigmoid Knotting (ISK). Although the frequency of ISK is unknown, adult males are more likely to experience it, and it typically manifests in regions with a high sigmoid volvulus incidence. There is debate concerning the cause of ISK. Abdominal ... Read more
CASE REPORT Updated Mar 11, 2024 PDF
World J Clin Case Rep Case Ser. 2024;4(1):WJCCRCS-04-1021 | Open Access
Argyri Papadimitriou, Julie Poisson, Benoît Rouiller, Grégoire Berthodand Michel Christodoulou
Introduction: Hidradenocarcinoma is a malignant lesion arising from the intradermal duct of eccrine or apocrine sweat glands. Extremely rare, the incidence of this lesion in the United States is 0.45 per million persons per year. Due to its rarity, treatment in advanced stages is not standardized. The prognosis remains unclear, with recent optimistic data reporting a 10-year Overall Survival (... Read more
CASE REPORT Updated Jan 22, 2024 PDF
World J Clin Case Rep Case Ser. 2023;3(2):WJCCRCS-03-1020 | Open Access
Ilgeldiev, Tabidze, Soeren Stoeckel, Diab, Labadze, Cipolla, Trifone, Hagen Rudolph and Lutz Mirow
Background: The inguinal region is an anatomically complex area where swellings are often interpreted as inguinal hernias. Inguinal hernia is one of the most common diagnoses in patients presenting with groin swelling. However, other pathologies can produce similar symptoms.
Objective: This case series aims to emphasize the importance of thorough differential diagnosis in patients with groin ... Read more
CASE SERIES Updated Dec 23, 2023 PDF
World J Clin Case Rep Case Ser. 2023;3(2):WJCCRCS-03-1019 | Open Access
Yu Fang, Ping Guo, Liang LV, Min Feng, Shanfei Cheng, Mincai Qian, Shikai Wang* and Huanxin Chen
Clozapine is the treatment choice for Treatment-Resistant Schizophrenia (TRS), but 40% to 70% patients with TRS remain inadequately treated despite clozapine treatment, known as Clozapine-Resistant Schizophrenia (CRS). CRS’s current treatment combines clozapine with other antipsychotics or physical therapy, but the outcome is still unsatisfactory. Blonanserin is a new atypical antipsychotic which processes advantages over other antipsychotics. We concurrent treated three ... Read more
CASE SERIES Updated Nov 15, 2023 PDF
World J Clin Case Rep Case Ser. 2023;3(2):WJCCRCS-03-1018 | Open Access
Ataki H, Amanzoui K, Mabchour M and Ezzouine H
Hemostasis disorders are frequently observed in intensive care. The objective of this study is to determine the incidence, etiologies and management to reduce the risk of Morbi-mortality. Through a retrospective, descriptive and analytical study of a series of 50 patients hospitalized in the medical intensive care unit from the Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, from 1st ... Read more
RESEARCH ARTICLE Updated Oct 11, 2023 PDF
World J Clin Case Rep Case Ser. 2023;3(2):WJCCRCS-03-1017 | Open Access
Henri Decloedt Lieke Dullens, Kevin Wetzels, Ann Vandeputte, Jan Decloedt and Nynke Willers
Mammary Paget’s Disease (MPD) is a malignant noninvasive proliferation of glandular epithelial cells (in situ carcinoma or DCIS) in the nipple. MPD is a rare presentation of Breast Cancer (BC), accounting for 1% to 3% of all BCs. Even rarer, secondary mammary MPD as a relapse of a primary BC is seen. If recognized and treated early, MPD is known ... Read more
CASE REPORT Updated Oct 06, 2023 PDF
World J Clin Case Rep Case Ser. 2023;3(1):WJCCRCS-03-1015 | Open Access
Nipun Bansal, Prashanth Adiga, Kishan Raj and Manjunath Shetty
Background: Nephroenteric and Nephrocutaneous fistulas occur rarely. The incidence of this condition has in recent times has declined due to advancement in treatment therapies. Currently, only a few cases have been reported in the literature.
Methods: We present largest single case series across the globe comprised of 6 patients treated at our hospital between 2016 and 2022, secondary to ... Read more
CASE SERIES Updated Apr 06, 2023 PDF
World J Clin Case Rep Case Ser. 2023;3(1):WJCCRCS-03-1014 | Open Access
Jang MJ, Kim JH, Han WH and Lee JH
With increase in the use of sodium-glucose cotransporter 2 inhibitors in patients with type 2 diabetes mellitus, the incidence of perioperative euglycemic diabetic ketoacidosis has been on the rise. The diagnosis of perioperative euglycemic DKA is a conundrum for physicians due to the absence of hyperglycemia and other perioperative complications should be excluded. Here, we report two cases of euglycemic DKA after ... Read more
CASE REPORT Updated Feb 04, 2023 PDF
World J Clin Case Rep Case Ser. 2023;3(1):WJCCRCS-03-1013 | Open Access
Zeynep Tuba Bahtiyarca, Yeşim Özge Gündüz and Ece Ünlü Akyüz
As a result of the escalating global epidemic of obesity, conservative and surgical interventions, and the incidence of secondary neurological complications in- volving the central and peripheral nervous systems, have increased. This case report presents a patient diagnosed with myelopathy and polyneuropathy after an uncontrolled rapid weight loss with a very low-calorie diet program. Our aim in presenting this case ... Read more
CASE REPORT Updated Jan 31, 2023 PDF
World J Clin Case Rep Case Ser. 2023;3(1):WJCCRCS-03-1012 | Open Access
Mohammadreza Shahidipak
The daily reports from the Mediterranean coast are the common heritage of the world. During his long journey on the western Mediterranean coast, Leo African recorded a large collection of daily reports on various topics including health and diseases in Fez, and in his own way, it is a valuable asset in genealogy and geographical distribution. It is a disease. ... Read more
SHORT COMMUNICATION Updated Jan 30, 2023 PDF
World J Clin Case Rep Case Ser. 2022;2(1):WJCCRCS-02-1011 | Open Access
Moumita Kundu, Bidisha Das and TK Chatterjee
Humanized monoclonal antibody called dostarlimab is developed as PD1 receptor antagonist to treat various malignancies. Jemperli, Glaxosmithkline (Dostar- limab) just received approval in the USA and EU for the treatment of adult patients with defective genes, (progressive endometrial cancer) based on results from the garnet trial. Clinical research depends on Treatment research, prevention research, diagnostic research, screening research, quality of ... Read more
MINI REVIEW Updated Dec 08, 2022 PDF
World J Clin Case Rep Case Ser. 2022;2(1):WJCCRCS-02-1010 | Open Access
Anisha Patel, S P Srinivas Nayak and Gunosindhu Chakraborthy
Hurler Syndrome, A hereditary sickness of the lysosome is a result of a deficiency in the enzyme alpha-L-iduronidase, which breaks down glycosaminoglycans (GAG or mucopolysaccharides). As a result, tissue harm from Dermatan sulphate and heparin sulphate worsens over time till death. Umbilical hernias are ventral hernias that arise at or across the umbilicus. This situation report describes the surgical treatment ... Read more
CASE REPORT Updated Nov 21, 2022 PDF
World J Clin Case Rep Case Ser. 2022;2(1):WJCCRCS-02-1009 | Open Access
Shaoqi Han, Jing Tu and Yifei Chen
Rationale: Diabetes is one of the most common diseases and is a severe threat to public health worldwide. Long-term chronic hyperglycemia can cause multisystem injuries, such as chronic progressive diseases, hypofunction, and failure of the eyes, nerves, cardiac system, and blood vessels. It can also cause acute severe metabolic disorders such as Diabetic Ketoacidosis (DKA) and hypertonic hyperglycemic ... Read more
CASE REPORT Updated Nov 07, 2022 PDF
World J Clin Case Rep Case Ser. 2022;2(1):WJCCRCS-02-1008 | Open Access
Niharika Raghavapuram and Talasila Narmada
Background: Two unusual case reports of polymyxin B induced hypotension
Case summary: Polymyxins are reintroduced for the treatment of MDR gram negative organisms, although sufficient data is available regarding the nephrotoxicity and neurotoxicity of poly B very few data is available regarding the cardiovascular effects of polymyxin B.
Case 1: A 51 years old female patient ... Read more
CASE SERIES Updated Sep 20, 2022 PDF
World J Clin Case Rep Case Ser. 2022;2(1):WJCCRCS-02-1007 | Open Access
Sevinc Kalin
Congenital anomalies and variations should be kept in mind when evaluating diseases in the pediatric patient group. A 12 years old girl presented with findings of a cut abdomen. Clinical and laboratory data were consistent with acute pancreatitis. Imaging findings showed a peristaltic cystic tissue with a thick wall and central lumen in the head of the pancreas. In the operation, ... Read more
CASE REPORT Updated Aug 03, 2022 PDF
World J Clin Case Rep Case Ser. 2022;2(1):WJCCRCS-02-1006 | Open Access
Lu YM, Yu CH and Wu HK
Background: Multilevel Spinal Epidural Abscess (SEA) is a rare and challenging disease. Delayed diagnosis and inadequate intervention may lead to irreversible paraplegia or even death. However, its insidious presentation and variable progression pattern makes early precise diagnosis challenging.
Purpose: To our knowledge, there is no article regarding to multi-level SEA treated with full endoscopic debridement. The ... Read more
CASE REPORT Updated Jul 25, 2022 PDF
World J Clin Case Rep Case Ser. 2021;1(1):WJCCRCS-01-1005 | Open Access
Shahrokh Sadeghi Boogar, Faezeh Sehatpour, Samin Ranjbar, Seyed Reza Kasaee, Sareh Mosleh-Shirazi, Farnaz Kamali Haghigh Shirazi and Rozita Sahraeyan
Diabetes Mellitus (DM) is one of the comorbidities that can increase the mortality rate of COVID-19 patients. The characteristics of patients who present with Diabetic Ketoacidosis (DKA) and COVID-19 co morbidity have not been reviewed sufficiently. In this study, we describe 7 patients admitted to our department with impression of DKA and concomitant COVID-19. Patients’ lab data, imaging and outcomes ... Read more
CASE SERIES Updated Oct 05, 2021 PDF
World J Clin Case Rep Case Ser. 2020;1(1):WJCCRCS-01-1004 | Open Access
Shiyin Luo, Tongjian Chui, Yongmei Dai, Chen Huang, Qianshun Chen and Xunyu Xu
Background: The first-line treatment for patients with advanced NSCLC with ROS-1 rearrangement is targeted therapy with first-generation ALK inhibitor. When leptomeningeal metastasis occurs, the treatment regimen for ROS-1-positive NSCLC patients is relatively limited. This study aimed to report the efficacy of lorlatinib combined with whole brain radiotherapy in an advanced NSCLC patient with leptomeningeal metastasis.
Case presentation: A 34... Read more
CASE REPORT Updated Dec 17, 2020 PDF
World J Clin Case Rep Case Ser. 2020;1(1):WJCCRCS-01-1003 | Open Access
Nnodim Johnkennedy, Nwaokoro Joakin Chidozie, Nwanguma Eberechi, Bako Hauwa, Ohalete Chinyere and Njoku-Obi Treasure
Aim: This study was done to determine levels of some adipokines (adiponectin and leptin) in diabetics.
Methods: The study involved 100 diabetics and 100 apparently normal subjects of the same age group 40-70. The levels of adiponectin and leptin were measured with Enzyme Immune Absorbent (ELISA) assay method.
Results: The level of leptin significantly increased in the diabetics when compared ... Read more
SHORT COMMUNICATION Updated Dec 07, 2020 PDF
World J Clin Case Rep Case Ser. 2020;1(1):WJCCRCS-01-1002 | Open Access
Alex Y Chen and Roderick V Dizon
Autoimmune encephalitis comprises a myriad of conditions due to autoantibodies against neuronal surface antigens. Etiologies and prognosis vary. Limbic encephalitis often has subacute manifestation with short-term memory loss, seizures, confusion, and psychiatric symptoms. Here, we presented a rare case of non-neoplastic ... Read more
CASE REPORT Updated Nov 30, 2020 PDF
World J Clin Case Rep Case Ser. 2020;1(1):WJCCRCS-01-1001 | Open Access
Jais Kumar Karmaniand Sheikh Farhan Athar
Various neurological features have been reported in association with Systemic Lupus Erythematosus (SLE) however, Guillaine Barre Syndrome (GBS) as a presenting feature of SLE appears to be rare. We report a patient presenting with GBS in whom lupus nephritis was subsequently diagnosed. Patient was treated with steroids and cyclophosphamide which resulted in improvement of both her neurological status and proteinuria.
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CASE REPORT Updated Aug 26, 2020 PDF